7ft4: Difference between revisions

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-'''Unreleased structure'''
-The entry 7ft4 is ON HOLD
+==SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z48847594==
+<StructureSection load='7ft4' size='340' side='right'caption='[[7ft4]], [[Resolution|resolution]] 2.17&Aring;' scene=''>
-Authors: Bradshaw, W.J., Katis, V.L., Bountra, C., von Delft, F., Brennan, P.E.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[7ft4]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7FT4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7FT4 FirstGlance]. <br>
-Description: SDCBP PanDDA analysis group deposition --The PDZ domans of SDCBP in complex with Z48847594
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ALA:ALANINE'>ALA</scene>, <scene name='pdbligand=DGL:D-GLUTAMIC+ACID'>DGL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GLY:GLYCINE'>GLY</scene>, <scene name='pdbligand=O0J:N-[4-(2-amino-1,3-thiazol-4-yl)phenyl]acetamide'>O0J</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ft4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ft4 OCA], [https://pdbe.org/7ft4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ft4 RCSB], [https://www.ebi.ac.uk/pdbsum/7ft4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ft4 ProSAT]</span></td></tr>
-[[Category: Katis, V.L]]
+</table>
-[[Category: Von Delft, F]]
+== Function ==
-[[Category: Bountra, C]]
+[https://www.uniprot.org/uniprot/SDCB1_HUMAN SDCB1_HUMAN] Seems to function as an adapter protein. In adherens junctions may function to couple syndecans to cytoskeletal proteins or signaling components. Seems to couple transcription factor SOX4 to the IL-5 receptor (IL5RA). May also play a role in vesicular trafficking. Seems to be required for the targeting of TGFA to the cell surface in the early secretory pathway.<ref>PMID:10230395</ref> <ref>PMID:11179419</ref> <ref>PMID:11498591</ref>
-[[Category: Brennan, P.E]]
+== References ==
-[[Category: Bradshaw, W.J]]
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Homo sapiens]]
+[[Category: Large Structures]]
+[[Category: Bountra C]]
+[[Category: Bradshaw WJ]]
+[[Category: Brennan PE]]
+[[Category: Katis VL]]
+[[Category: Von Delft F]]