7z8q: Difference between revisions

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'''Unreleased structure'''


The entry 7z8q is ON HOLD  until Paper Publication
==Cryo-EM structure of Mycobacterium tuberculosis RNA polymerase core==
 
<StructureSection load='7z8q' size='340' side='right'caption='[[7z8q]], [[Resolution|resolution]] 4.08&Aring;' scene=''>
Authors: Brodolin, K.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[7z8q]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7Z8Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7Z8Q FirstGlance]. <br>
Description: Cryo-EM structure of Mycobacterium tuberculosis RNA polymerase core
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
[[Category: Unreleased Structures]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7z8q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7z8q OCA], [https://pdbe.org/7z8q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7z8q RCSB], [https://www.ebi.ac.uk/pdbsum/7z8q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7z8q ProSAT]</span></td></tr>
[[Category: Brodolin, K]]
</table>
== Function ==
[https://www.uniprot.org/uniprot/RPOA_MYCTU RPOA_MYCTU] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.[HAMAP-Rule:MF_00059]<ref>PMID:22570422</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mycobacterium tuberculosis H37Rv]]
[[Category: Brodolin K]]

Revision as of 09:44, 8 February 2023

Cryo-EM structure of Mycobacterium tuberculosis RNA polymerase coreCryo-EM structure of Mycobacterium tuberculosis RNA polymerase core

Structural highlights

7z8q is a 5 chain structure with sequence from Mycobacterium tuberculosis H37Rv. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

RPOA_MYCTU DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.[HAMAP-Rule:MF_00059][1]

References

  1. ↑ Hu Y, Morichaud Z, Chen S, Leonetti JP, Brodolin K. Mycobacterium tuberculosis RbpA protein is a new type of transcriptional activator that stabilizes the sigma A-containing RNA polymerase holoenzyme. Nucleic Acids Res. 2012 Aug;40(14):6547-57. doi: 10.1093/nar/gks346. Epub 2012, May 8. PMID:22570422 doi:http://dx.doi.org/10.1093/nar/gks346

7z8q, resolution 4.08Å

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OCA
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