4oq0: Difference between revisions
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==Crystal structure of stabilized TEM-1 beta-lactamase variant v.13 carrying R164S/G238S mutation in complex with boron-based inhibitor EC25== | ==Crystal structure of stabilized TEM-1 beta-lactamase variant v.13 carrying R164S/G238S mutation in complex with boron-based inhibitor EC25== | ||
<StructureSection load='4oq0' size='340' side='right' caption='[[4oq0]], [[Resolution|resolution]] 1.42Å' scene=''> | <StructureSection load='4oq0' size='340' side='right'caption='[[4oq0]], [[Resolution|resolution]] 1.42Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4oq0]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[4oq0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OQ0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4OQ0 FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2UL:3-[(2R)-2-{[(2R)-2-AMINO-2-PHENYLACETYL]AMINO}-2-(DIHYDROXYBORANYL)ETHYL]BENZOIC+ACID'>2UL</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2UL:3-[(2R)-2-{[(2R)-2-AMINO-2-PHENYLACETYL]AMINO}-2-(DIHYDROXYBORANYL)ETHYL]BENZOIC+ACID'>2UL</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4oq0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4oq0 OCA], [https://pdbe.org/4oq0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4oq0 RCSB], [https://www.ebi.ac.uk/pdbsum/4oq0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4oq0 ProSAT]</span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/Q8KMX3_ECOLX Q8KMX3_ECOLX] | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</div> | </div> | ||
<div class="pdbe-citations 4oq0" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 4oq0" style="background-color:#fffaf0;"></div> | ||
==See Also== | |||
*[[Beta-lactamase 3D structures|Beta-lactamase 3D structures]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Escherichia coli]] | ||
[[Category: Dellus-Gur | [[Category: Large Structures]] | ||
[[Category: Elias | [[Category: Dellus-Gur E]] | ||
[[Category: Fraser | [[Category: Elias M]] | ||
[[Category: Tawfik | [[Category: Fraser JS]] | ||
[[Category: Tawfik DS]] | |||