8c77: Difference between revisions

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'''Unreleased structure'''


The entry 8c77 is ON HOLD
==Human cathepsin L after reaction with the thiocarbazate inhibitor CID 16725315==
 
<StructureSection load='8c77' size='340' side='right'caption='[[8c77]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
Authors: Falke, S., Lieske, J., Guenther, S., Reinke, P.Y.A., Ewert, W., Loboda, J., Karnicar, K., Usenik, A., Lindic, N., Sekirnik, A., Chapman, H.N., Hinrichs, W., Turk, D., Meents, A.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[8c77]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8C77 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8C77 FirstGlance]. <br>
Description: Human cathepsin L after reaction with the thiocarbazate inhibitor CID 16725315
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=TXH:~{tert}-butyl+~{N}-[(2~{S})-3-(1~{H}-indol-3-yl)-1-(2-methanoylhydrazinyl)-1-oxidanylidene-propan-2-yl]carbamate'>TXH</scene></td></tr>
[[Category: Unreleased Structures]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8c77 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8c77 OCA], [https://pdbe.org/8c77 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8c77 RCSB], [https://www.ebi.ac.uk/pdbsum/8c77 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8c77 ProSAT]</span></td></tr>
[[Category: Lieske, J]]
</table>
[[Category: Hinrichs, W]]
== Function ==
[[Category: Usenik, A]]
[https://www.uniprot.org/uniprot/CATL1_HUMAN CATL1_HUMAN] Important for the overall degradation of proteins in lysosomes.
[[Category: Sekirnik, A]]
__TOC__
[[Category: Meents, A]]
</StructureSection>
[[Category: Ewert, W]]
[[Category: Homo sapiens]]
[[Category: Chapman, H.N]]
[[Category: Large Structures]]
[[Category: Turk, D]]
[[Category: Chapman HN]]
[[Category: Lindic, N]]
[[Category: Ewert W]]
[[Category: Karnicar, K]]
[[Category: Falke S]]
[[Category: Loboda, J]]
[[Category: Guenther S]]
[[Category: Falke, S]]
[[Category: Hinrichs W]]
[[Category: Guenther, S]]
[[Category: Karnicar K]]
[[Category: Reinke, P.Y.A]]
[[Category: Lieske J]]
[[Category: Lindic N]]
[[Category: Loboda J]]
[[Category: Meents A]]
[[Category: Reinke PYA]]
[[Category: Sekirnik A]]
[[Category: Turk D]]
[[Category: Usenik A]]

Revision as of 09:34, 25 January 2023

Human cathepsin L after reaction with the thiocarbazate inhibitor CID 16725315Human cathepsin L after reaction with the thiocarbazate inhibitor CID 16725315

Structural highlights

8c77 is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:, , , , , ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

CATL1_HUMAN Important for the overall degradation of proteins in lysosomes.

8c77, resolution 1.70Å

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