VEGF signaling pathway: Difference between revisions
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[[Vascular Endothelial Growth Factor]]s (VEGFs) are a class of proteins that regulate vascular development in embryos and angiogenesis in adult mammals after sustaining an injury or notably in [[Cancer|cancerous]] tumors. A number of structural studies have been conducted on VEGF and its receptors (VEGFRs) to better understand the VEGF-VEGFR interaction and how the signal cascade originating from this interaction leads to a number of biological features. VEGF and its receptors have been closely looked at for their potential use as targets for pharmaceutical medicine with some success. The VEGF family contains VEGF-A which mediates increased vascular permeability, VEGF-B which is a growth factor, VEGF-C is active in angiogenesis, VEGF-E is found in viruses and VEGF-F in snake venom.<br /> For additional information see:<br /> | [[Vascular Endothelial Growth Factor]]s (VEGFs) are a class of proteins that regulate vascular development in embryos and angiogenesis in adult mammals after sustaining an injury or notably in [[Cancer|cancerous]] tumors. A number of structural studies have been conducted on VEGF and its receptors (VEGFRs) to better understand the VEGF-VEGFR interaction and how the signal cascade originating from this interaction leads to a number of biological features. VEGF and its receptors have been closely looked at for their potential use as targets for pharmaceutical medicine with some success. The VEGF family contains VEGF-A which mediates increased vascular permeability, VEGF-B which is a growth factor, VEGF-C is active in angiogenesis, VEGF-E is found in viruses and VEGF-F in snake venom.<br /> For additional information see:<br /> | ||
[[VEGFR]]<br /> | [[VEGFR]]<br /> | ||
[[VEGF IN COMPLEX WITH A NEUTRALIZING ANTIBODY]].. | [[VEGF IN COMPLEX WITH A NEUTRALIZING ANTIBODY]] | ||
[[VEGF signaling pathway]].. | |||
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