4o7x: Difference between revisions

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 ==Crystal structure of human ALKBH5 in complex with Mn2+==
-<StructureSection load='4o7x' size='340' side='right' caption='[[4o7x]], [[Resolution|resolution]] 1.78&Aring;' scene=''>
+<StructureSection load='4o7x' size='340' side='right'caption='[[4o7x]], [[Resolution|resolution]] 1.78&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[4o7x]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4O7X OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4O7X FirstGlance]. <br>
+<table><tr><td colspan='2'>[[4o7x]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4O7X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4O7X FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
-<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ABH5, ALKBH5, OFOXD1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4o7x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4o7x OCA], [https://pdbe.org/4o7x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4o7x RCSB], [https://www.ebi.ac.uk/pdbsum/4o7x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4o7x ProSAT]</span></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4o7x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4o7x OCA], [http://pdbe.org/4o7x PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4o7x RCSB], [http://www.ebi.ac.uk/pdbsum/4o7x PDBsum]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/ALKB5_HUMAN ALKB5_HUMAN]] Dioxygenase that demethylates RNA by oxidative demethylation: specifically demethylates N(6)-methyladenosine (m(6)A) RNA, the most prevalent internal modification of messenger RNA (mRNA) in higher eukaryotes. Requires molecular oxygen, alpha-ketoglutarate and iron. Demethylation of m(6)A mRNA affects mRNA processing and export and is required for spermatogenesis.<ref>PMID:21264265</ref> <ref>PMID:23177736</ref>
+[https://www.uniprot.org/uniprot/ALKB5_HUMAN ALKB5_HUMAN] Dioxygenase that demethylates RNA by oxidative demethylation: specifically demethylates N(6)-methyladenosine (m(6)A) RNA, the most prevalent internal modification of messenger RNA (mRNA) in higher eukaryotes. Requires molecular oxygen, alpha-ketoglutarate and iron. Demethylation of m(6)A mRNA affects mRNA processing and export and is required for spermatogenesis.<ref>PMID:21264265</ref> <ref>PMID:23177736</ref>
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
@@ Line 20: / Line 20: @@
 ==See Also==
-*[[Dioxygenase|Dioxygenase]]
+*[[Dioxygenase 3D structures|Dioxygenase 3D structures]]
 == References ==
 <references/>
 __TOC__
 </StructureSection>
-[[Category: Human]]
+[[Category: Homo sapiens]]
-[[Category: Chen, Z]]
+[[Category: Large Structures]]
-[[Category: Feng, C]]
+[[Category: Chen Z]]
-[[Category: Liu, Y]]
+[[Category: Feng C]]
-[[Category: 6-methyl adenosine]]
+[[Category: Liu Y]]
-[[Category: Demethylation]]
-[[Category: Human dioxygenase]]
-[[Category: Metal-binding]]
-[[Category: Nucleus]]
-[[Category: Oxidoreductase]]
-[[Category: Protein/dna interaction]]
-[[Category: Rna repair]]