4ntf: Difference between revisions

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<StructureSection load='4ntf' size='340' side='right'caption='[[4ntf]], [[Resolution|resolution]] 2.65&Aring;' scene=''>
<StructureSection load='4ntf' size='340' side='right'caption='[[4ntf]], [[Resolution|resolution]] 2.65&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4ntf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NTF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4NTF FirstGlance]. <br>
<table><tr><td colspan='2'>[[4ntf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NTF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4NTF FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GTX:S-HEXYLGLUTATHIONE'>GTX</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>, <scene name='pdbligand=PLM:PALMITIC+ACID'>PLM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GTX:S-HEXYLGLUTATHIONE'>GTX</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>, <scene name='pdbligand=PLM:PALMITIC+ACID'>PLM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4nta|4nta]], [[4ntb|4ntb]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ntf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ntf OCA], [https://pdbe.org/4ntf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ntf RCSB], [https://www.ebi.ac.uk/pdbsum/4ntf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ntf ProSAT]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Ltc4s ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Leukotriene-C(4)_synthase Leukotriene-C(4) synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.4.1.20 4.4.1.20] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ntf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ntf OCA], [http://pdbe.org/4ntf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ntf RCSB], [http://www.ebi.ac.uk/pdbsum/4ntf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ntf ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/LTC4S_MOUSE LTC4S_MOUSE]] Catalyzes the conjugation of leukotriene A4 with reduced glutathione to form leukotriene C4.  
[https://www.uniprot.org/uniprot/LTC4S_MOUSE LTC4S_MOUSE] Catalyzes the conjugation of leukotriene A4 with reduced glutathione to form leukotriene C4.


==See Also==
==See Also==
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Lk3 transgenic mice]]
[[Category: Mus musculus]]
[[Category: Haeggstrom, J Z]]
[[Category: Haeggstrom JZ]]
[[Category: Niegowski, D]]
[[Category: Niegowski D]]
[[Category: Rinaldo-Matthis, A]]
[[Category: Rinaldo-Matthis A]]
[[Category: Lipid biosynthesis]]
[[Category: Lyase]]
[[Category: Product analog]]

Revision as of 11:38, 18 January 2023

Mus Musculus LTC4 synthase in S-hexyl-GSH complex formMus Musculus LTC4 synthase in S-hexyl-GSH complex form

Structural highlights

4ntf is a 1 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:, , ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

LTC4S_MOUSE Catalyzes the conjugation of leukotriene A4 with reduced glutathione to form leukotriene C4.

See Also

4ntf, resolution 2.65Å

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