Phospholipase C: Difference between revisions
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*'''Phospholipase C δ''' is critical for Ca+2 homeostasis. | *'''Phospholipase C δ''' is critical for Ca+2 homeostasis. | ||
*'''Phospholipase C ε''' is an effector for Ras. | *'''Phospholipase C ε''' is an effector for Ras. | ||
*'''Phosphatidylinositol-specific phospholipase C''' (PIPLC) catalyzes the hydrolysis of phosphatidylinositol into inositol triphosphate and deacylglycerol. PIPLC functions at the plasma membrane. PIPLC can release phosphatidylinositol-linked proteins (i.e., acetylcholinesterase) from the membrane by enzymatically cleaving their GPI anchor. <ref>PMID:11249190</ref> | *'''Phosphatidylinositol-specific phospholipase C''' (PIPLC) catalyzes the hydrolysis of phosphatidylinositol into inositol triphosphate and deacylglycerol. PIPLC functions at the plasma membrane. PIPLC can release phosphatidylinositol-linked proteins (i.e., acetylcholinesterase) from the membrane by enzymatically cleaving their GPI anchor. <ref>PMID:11249190</ref>. See also [[IP3 is second messenger]]. | ||
== Disease == | == Disease == | ||