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==Crystal structure of a trap periplasmic solute binding protein from Desulfovibrio alaskensis G20 (DDE_0634), target EFI-510102, with bound d-tryptophan== | ==Crystal structure of a trap periplasmic solute binding protein from Desulfovibrio alaskensis G20 (DDE_0634), target EFI-510102, with bound d-tryptophan== | ||
<StructureSection load='4nap' size='340' side='right' caption='[[4nap]], [[Resolution|resolution]] 2.30Å' scene=''> | <StructureSection load='4nap' size='340' side='right'caption='[[4nap]], [[Resolution|resolution]] 2.30Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4nap]] is a 4 chain structure with sequence from [ | <table><tr><td colspan='2'>[[4nap]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Oleidesulfovibrio_alaskensis_G20 Oleidesulfovibrio alaskensis G20]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NAP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4NAP FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DTR:D-TRYPTOPHAN'>DTR</scene> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DTR:D-TRYPTOPHAN'>DTR</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4nap FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nap OCA], [https://pdbe.org/4nap PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4nap RCSB], [https://www.ebi.ac.uk/pdbsum/4nap PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4nap ProSAT]</span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/DCTP2_OLEA2 DCTP2_OLEA2] Solute-binding protein that binds indole-3-pyruvate and indole-3-acetate (in vitro). Can also bind D-tryptophan (in vitro), but that is probably not a physiological ligand (PubMed:25540822). Probably part of a tripartite ATP-independent periplasmic (TRAP) transport system that mediates solute transport into the cytoplasm.<ref>PMID:25540822</ref> | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Oleidesulfovibrio alaskensis G20]] | ||
[[Category: | [[Category: Al Obaidi NF]] | ||
[[Category: | [[Category: Almo SC]] | ||
[[Category: | [[Category: Attonito JD]] | ||
[[Category: | [[Category: Chowdhury S]] | ||
[[Category: | [[Category: Evans B]] | ||
[[Category: | [[Category: Gerlt JA]] | ||
[[Category: Hillerich | [[Category: Hillerich B]] | ||
[[Category: Imker | [[Category: Imker HJ]] | ||
[[Category: Love | [[Category: Love J]] | ||
[[Category: Morisco | [[Category: Morisco LL]] | ||
[[Category: | [[Category: Scott Glenn A]] | ||
[[Category: Seidel | [[Category: Seidel RD]] | ||
[[Category: Sojitra | [[Category: Sojitra S]] | ||
[[Category: Stead | [[Category: Stead M]] | ||
[[Category: Vetting | [[Category: Vetting MW]] | ||
[[Category: Wasserman | [[Category: Wasserman SR]] | ||