Reverse Krebs cycle: Difference between revisions

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Oxaloacetate + NADH/H+ -> Malate + NAD+
Oxaloacetate + NADH/H+ -> Malate + NAD+
*Fumarate to succinate, catalyzed by an oxidoreductase, Fumarate reductase (''e.g.'' [[1d4c]])
 
*<scene name='43/430893/Cv/11'>Fumarate</scene> to <scene name='43/430893/Cv/10'>succinate</scene>, catalyzed by an [[oxidoreductase]], Fumarate reductase (''e.g.'' [[1d4c]])


Fumarate + FADH2 <=> Succinate + FAD
Fumarate + FADH2 <=> Succinate + FAD

Revision as of 16:43, 5 January 2023

The reverse Krebs cycle (also known as the reverse tricarboxylic acid cycle, the reverse TCA cycle, or the reverse citric acid cycle, or the reductive tricarboxylic acid cycle, or the reductive TCA cycle) is a sequence of chemical reactions that are used by some bacteria to produce carbon compounds from carbon dioxide and water by the use of energy-rich reducing agents as electron donors. See also [1] and Carbon Fixation.

The cycle involves the biosynthesis of from two molecules of CO2. The key steps of the reverse Krebs cycle are:

  • to , using NADH + H+

Oxaloacetate + NADH/H+ -> Malate + NAD+

Fumarate + FADH2 <=> Succinate + FAD


ATP-citrate synthase complex with ADP (stick model), tartrate and Mg+2 ions (green), 3pff

Drag the structure with the mouse to rotate

ReferencesReferences

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Alexander Berchansky