4n5t: Difference between revisions

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 ==The 1.7A Crystal Structure of MDMX with a Stapled Peptide, ATSP-7041==
-<StructureSection load='4n5t' size='340' side='right' caption='[[4n5t]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
+<StructureSection load='4n5t' size='340' side='right'caption='[[4n5t]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[4n5t]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Brachidanio_rerio Brachidanio rerio]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4N5T OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4N5T FirstGlance]. <br>
+<table><tr><td colspan='2'>[[4n5t]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Danio_rerio Danio rerio] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4N5T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4N5T FirstGlance]. <br>
-</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=0EH:(2R)-2-AMINO-2-METHYLNONANOIC+ACID'>0EH</scene>, <scene name='pdbligand=2JH:3-CYCLOBUTYL-L-ALANINE'>2JH</scene>, <scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=MK8:2-METHYL-L-NORLEUCINE'>MK8</scene></td></tr>
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0EH:(2R)-2-AMINO-2-METHYLNONANOIC+ACID'>0EH</scene>, <scene name='pdbligand=2JH:3-CYCLOBUTYL-L-ALANINE'>2JH</scene>, <scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=MK8:2-METHYL-L-NORLEUCINE'>MK8</scene></td></tr>
-<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">mdm4, mdmx ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7955 Brachidanio rerio])</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4n5t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4n5t OCA], [https://pdbe.org/4n5t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4n5t RCSB], [https://www.ebi.ac.uk/pdbsum/4n5t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4n5t ProSAT]</span></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4n5t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4n5t OCA], [http://pdbe.org/4n5t PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4n5t RCSB], [http://www.ebi.ac.uk/pdbsum/4n5t PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4n5t ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/MDM4_DANRE MDM4_DANRE]] Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain (By similarity).
+[https://www.uniprot.org/uniprot/MDM4_DANRE MDM4_DANRE] Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain (By similarity).
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
@@ Line 19: / Line 18: @@
 </div>
 <div class="pdbe-citations 4n5t" style="background-color:#fffaf0;"></div>
+==See Also==
+*[[MDM4|MDM4]]
 == References ==
 <references/>
 __TOC__
 </StructureSection>
-[[Category: Brachidanio rerio]]
+[[Category: Danio rerio]]
-[[Category: Graves, B J]]
+[[Category: Large Structures]]
-[[Category: Janson, C A]]
+[[Category: Synthetic construct]]
-[[Category: Lukacs, C]]
+[[Category: Graves BJ]]
-[[Category: Apoptosis]]
+[[Category: Janson CA]]
-[[Category: Cell cycle]]
+[[Category: Lukacs C]]
-[[Category: Cell cycle-cell cycle inhibitor complex]]
-[[Category: Mdm4]]
-[[Category: Nucleus]]
-[[Category: P53]]
-[[Category: P53 antagonist]]