4mrn: Difference between revisions
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==Structure of a bacterial Atm1-family ABC transporter== | ==Structure of a bacterial Atm1-family ABC transporter== | ||
<StructureSection load='4mrn' size='340' side='right' caption='[[4mrn]], [[Resolution|resolution]] 2.50Å' scene=''> | <StructureSection load='4mrn' size='340' side='right'caption='[[4mrn]], [[Resolution|resolution]] 2.50Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4mrn]] is a 2 chain structure with sequence from [ | <table><tr><td colspan='2'>[[4mrn]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Novosphingobium_aromaticivorans_DSM_12444 Novosphingobium aromaticivorans DSM 12444]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MRN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4MRN FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=LDA:LAURYL+DIMETHYLAMINE-N-OXIDE'>LDA</scene>, <scene name='pdbligand= | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LDA:LAURYL+DIMETHYLAMINE-N-OXIDE'>LDA</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4mrn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mrn OCA], [https://pdbe.org/4mrn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4mrn RCSB], [https://www.ebi.ac.uk/pdbsum/4mrn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4mrn ProSAT]</span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/ATM1_NOVAD ATM1_NOVAD] Mediates the ATP-dependent export of glutathione-conjugated substrates, such as heavy metal-glutathione conjugates. ATP hydrolysis is stimulated by glutathione binding. Protects cells against toxic heavy metal ions, such as silver and mercury ions. May also mediate the transport of glutathione-conjugated aromatic hydrocarbons, such as dinitrobenzene.<ref>PMID:24604198</ref> | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Lee | [[Category: Novosphingobium aromaticivorans DSM 12444]] | ||
[[Category: Lewinson | [[Category: Lee JY]] | ||
[[Category: Rees | [[Category: Lewinson O]] | ||
[[Category: Yang | [[Category: Rees DC]] | ||
[[Category: Zhitnitsky | [[Category: Yang JG]] | ||
[[Category: Zhitnitsky D]] | |||