4lwf: Difference between revisions

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<StructureSection load='4lwf' size='340' side='right'caption='[[4lwf]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
<StructureSection load='4lwf' size='340' side='right'caption='[[4lwf]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4lwf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LWF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4LWF FirstGlance]. <br>
<table><tr><td colspan='2'>[[4lwf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LWF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4LWF FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FJ3:4-(5-AMINO-1,2-OXAZOL-3-YL)-6-(PROPAN-2-YL)BENZENE-1,3-DIOL'>FJ3</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FJ3:4-(5-AMINO-1,2-OXAZOL-3-YL)-6-(PROPAN-2-YL)BENZENE-1,3-DIOL'>FJ3</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4lwe|4lwe]], [[4lwg|4lwg]], [[4lwh|4lwh]], [[4lwi|4lwi]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4lwf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lwf OCA], [https://pdbe.org/4lwf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4lwf RCSB], [https://www.ebi.ac.uk/pdbsum/4lwf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4lwf ProSAT]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HSP90AA1, HSP90A, HSPC1, HSPCA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4lwf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lwf OCA], [http://pdbe.org/4lwf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4lwf RCSB], [http://www.ebi.ac.uk/pdbsum/4lwf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4lwf ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/HS90A_HUMAN HS90A_HUMAN]] Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.<ref>PMID:15937123</ref> <ref>PMID:11274138</ref>
[https://www.uniprot.org/uniprot/HS90A_HUMAN HS90A_HUMAN] Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.<ref>PMID:15937123</ref> <ref>PMID:11274138</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
*[[Heat Shock Proteins|Heat Shock Proteins]]
*[[Heat Shock Protein structures|Heat Shock Protein structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: He, J]]
[[Category: He J]]
[[Category: Li, J]]
[[Category: Li J]]
[[Category: Shi, F]]
[[Category: Shi F]]
[[Category: Xiong, B]]
[[Category: Xiong B]]
[[Category: Atp binding]]
[[Category: Chaperone]]
[[Category: Molecularchaperone]]
[[Category: Rossmann fold]]

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