1llm: Difference between revisions

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<StructureSection load='1llm' size='340' side='right'caption='[[1llm]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
<StructureSection load='1llm' size='340' side='right'caption='[[1llm]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1llm]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LLM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1LLM FirstGlance]. <br>
<table><tr><td colspan='2'>[[1llm]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus] and [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LLM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1LLM FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1aay|1aay]], [[1zaa|1zaa]], [[1ysa|1ysa]], [[1g2d|1g2d]], [[1g2f|1g2f]]</div></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1llm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1llm OCA], [https://pdbe.org/1llm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1llm RCSB], [https://www.ebi.ac.uk/pdbsum/1llm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1llm ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1llm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1llm OCA], [https://pdbe.org/1llm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1llm RCSB], [https://www.ebi.ac.uk/pdbsum/1llm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1llm ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/EGR1_MOUSE EGR1_MOUSE]] Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-CGCCCCCGC-3'(EGR-site). Activates the transcription of target genes whose products are required for mitogenesis and differentiation.  
[https://www.uniprot.org/uniprot/EGR1_MOUSE EGR1_MOUSE] Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-CGCCCCCGC-3'(EGR-site). Activates the transcription of target genes whose products are required for mitogenesis and differentiation.[https://www.uniprot.org/uniprot/GCN4_YEAST GCN4_YEAST] Is a transcription factor that is responsible for the activation of more than 30 genes required for amino acid or for purine biosynthesis in response to amino acid or purine starvation. Binds and recognize the DNA sequence: 5'-TGA[CG]TCA-3'.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Lk3 transgenic mice]]
[[Category: Mus musculus]]
[[Category: Grant, R A]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Pabo, C O]]
[[Category: Grant RA]]
[[Category: Wolfe, S A]]
[[Category: Pabo CO]]
[[Category: Dimerization]]
[[Category: Wolfe SA]]
[[Category: Dna recognition]]
[[Category: Leucine zipper]]
[[Category: Structure-based design]]
[[Category: Transcription-dna complex]]
[[Category: Zinc finger]]

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