1enw: Difference between revisions
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==ELONGATION FACTOR TFIIS DOMAIN II== | ==ELONGATION FACTOR TFIIS DOMAIN II== | ||
<StructureSection load='1enw' size='340' side='right'caption='[[1enw | <StructureSection load='1enw' size='340' side='right'caption='[[1enw]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1enw]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[1enw]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ENW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ENW FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1enw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1enw OCA], [https://pdbe.org/1enw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1enw RCSB], [https://www.ebi.ac.uk/pdbsum/1enw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1enw ProSAT]</span></td></tr> | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1enw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1enw OCA], [https://pdbe.org/1enw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1enw RCSB], [https://www.ebi.ac.uk/pdbsum/1enw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1enw ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/TFS2_YEAST TFS2_YEAST] Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus. Can promote the transfer of one strand of a double-stranded DNA molecule to a homologous single strand and thus may be involved in recombination. | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: | [[Category: Saccharomyces cerevisiae]] | ||
[[Category: | [[Category: Arrowsmith CH]] | ||
[[Category: | [[Category: Awrey DE]] | ||
[[Category: | [[Category: Edwards AM]] | ||
[[Category: | [[Category: Morin PE]] | ||