Cytochrome P450 3D structures: Difference between revisions
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**[[5l91]], [[5l92]] - BmP450 CYP109E1 + corticosterone<br /> | **[[5l91]], [[5l92]] - BmP450 CYP109E1 + corticosterone<br /> | ||
**[[5l94]] - BmP450 CYP109E1 + testosterone<br /> | **[[5l94]] - BmP450 CYP109E1 + testosterone<br /> | ||
**[[7f3h]] - P450 heme domain – Deinococcus aerius<br /> | **[[7f3h]] - P450 heme domain – ''Deinococcus aerius''<br /> | ||
**[[7f3w]] - P450 heme domain – Deinococcus apachensis<br /> | **[[7f3w]] - P450 heme domain – ''Deinococcus apachensis''<br /> | ||
*Eukaryote P450 Cyp51 or lanosterol 14-alpha demethylase | *Eukaryote P450 Cyp51 or lanosterol 14-alpha demethylase | ||
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**[[4zdy]], [[4zdz]], [[4ze0]], [[4ze1]], [[4ze2]], [[4ze3]], [[5ese]], [[5esf]], [[5esg]], [[5esh]], [[5esj]], [[5esk]], [[5esl]], [[5esm]], [[7ry8]], [[7ry9]], [[7rya]], [[7ryb]] – yCyp51 (mutant) + drug<br /> | **[[4zdy]], [[4zdz]], [[4ze0]], [[4ze1]], [[4ze2]], [[4ze3]], [[5ese]], [[5esf]], [[5esg]], [[5esh]], [[5esj]], [[5esk]], [[5esl]], [[5esm]], [[7ry8]], [[7ry9]], [[7rya]], [[7ryb]] – yCyp51 (mutant) + drug<br /> | ||
**[[4lxj]] – yCyp51 + lanosterol<br /> | **[[4lxj]] – yCyp51 + lanosterol<br /> | ||
**[[5v5z]] – CaP450 CYP51 – Candida albicans<br /> | **[[5v5z]] – CaP450 CYP51 – ''Candida albicans''<br /> | ||
**[[5tz1]] – CaP450 CYP51 + drug <br /> | **[[5tz1]] – CaP450 CYP51 + drug <br /> | ||
**[[5fsa]] – CaP450 CYP51 (mutant) + drug <br /> | **[[5fsa]] – CaP450 CYP51 (mutant) + drug <br /> | ||
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*Bacterial P450 Cyp51 or lanosterol 14-alpha demethylase | *Bacterial P450 Cyp51 or lanosterol 14-alpha demethylase | ||
**[[6mi0]], [[7jj1]]– McP450 CYP51 – Methylcoccus capsulatus<br /> | **[[6mi0]], [[7jj1]]– McP450 CYP51 – ''Methylcoccus capsulatus''<br /> | ||
**[[7tef]] – MmP450 CYP51B1 – Mycobacterium marinum<br /> | **[[7tef]] – MmP450 CYP51B1 – ''Mycobacterium marinum''<br /> | ||
**[[3g1q]] – TbP450 CYP51 – Trypanosoma brucei<br /> | **[[3g1q]] – TbP450 CYP51 – ''Trypanosoma brucei''<br /> | ||
**[[5jlc]] – P450 CYP51 – Candida glabrata<br /> | **[[5jlc]] – P450 CYP51 – ''Candida glabrata<''br /> | ||
**[[4bmm]], [[4by0]], [[4c0c]], [[4c27]], [[4c28]], [[4coh]], [[4uqh]], [[4uvr]] – P450 CYP51 + inhibitor – Trypanosoma cruzi<br /> | **[[4bmm]], [[4by0]], [[4c0c]], [[4c27]], [[4c28]], [[4coh]], [[4uqh]], [[4uvr]] – P450 CYP51 + inhibitor – ''Trypanosoma cruzi''<br /> | ||
**[[6fmo]] – P450 CYP51 (mutant) + obtosifoliol <br /> | **[[6fmo]] – P450 CYP51 (mutant) + obtosifoliol <br /> | ||
**[[6mcw]] – McP450 CYP51 + detergent <br /> | **[[6mcw]] – McP450 CYP51 + detergent <br /> | ||
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**[[3gw9]], [[4bjk]], [[4g3j]], [[4g7g]] – TbP450 CYP51 + inhibitor<br /> | **[[3gw9]], [[4bjk]], [[4g3j]], [[4g7g]] – TbP450 CYP51 + inhibitor<br /> | ||
**[[3p99]] – TbP450 CYP51 + lanosterol derivative<br /> | **[[3p99]] – TbP450 CYP51 + lanosterol derivative<br /> | ||
**[[6ay4]], [[6ayb]], [[6ayc]] – NfP450 CYP51 + drug – Naegleria fowleri<br /> | **[[6ay4]], [[6ayb]], [[6ayc]] – NfP450 CYP51 + drug – ''Naegleria fowleri''<br /> | ||
**[[3l4d]] – P450 CYP51 + drug – Leishmania infantum<br /> | **[[3l4d]] – P450 CYP51 + drug – ''Leishmania infantum''<br /> | ||
* Other CYPs | * Other CYPs | ||
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**[[1wiy]] – TtP450 – ''Thermus thermophilus''<br /> | **[[1wiy]] – TtP450 – ''Thermus thermophilus''<br /> | ||
**[[4e2p]], [[5xw2]] - P450 – ''Streptococcus himastatinicus''<br /> | **[[4e2p]], [[5xw2]] - P450 – ''Streptococcus himastatinicus''<br /> | ||
**[[6g5q]], [[6g5o]] - P450 – Zobellia galactanivorans<br /> | **[[6g5q]], [[6g5o]] - P450 – ''Zobellia galactanivorans''<br /> | ||
**[[5ysm]] – AmP450 – Amycolatopsis mediterranei<br /> | **[[5ysm]] – AmP450 – ''Amycolatopsis mediterranei''<br /> | ||
**[[6f0c]], [[6f0b]] - P450 TXTC – Streptomyces acidiscabies<br /> | **[[6f0c]], [[6f0b]] - P450 TXTC – ''Streptomyces acidiscabies''<br /> | ||
**[[5gwe]], [[7ccf]] – CgP450 CreJ – Corynebacterium glutamicum<br /> | **[[5gwe]], [[7ccf]] – CgP450 CreJ – ''Corynebacterium glutamicum''<br /> | ||
**[[5y1i]] - P450 GFSF – Streptomyces graminofaciens<br /> | **[[5y1i]] - P450 GFSF – ''Streptomyces graminofaciens''<br /> | ||
**[[1cpt]] – PsP450 TERP - ''Pseudomonas sp.''<br /> | **[[1cpt]] – PsP450 TERP - ''Pseudomonas sp.''<br /> | ||
**[[4l0e]], [[4l0f]] - StP450 SKY32– ''Streptomyces''<br /> | **[[4l0e]], [[4l0f]] - StP450 SKY32– ''Streptomyces''<br /> | ||
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**[[3a4z]], [[5gnm]], [[5gnl]] - PaP450 VDH (mutant)<br /> | **[[3a4z]], [[5gnm]], [[5gnl]] - PaP450 VDH (mutant)<br /> | ||
**[[3qi8]] – P450 – synthetic<br /> | **[[3qi8]] – P450 – synthetic<br /> | ||
**[[3g1q]] – TbP450 CYP51 – Trypanosoma brucei<br /> | **[[3g1q]] – TbP450 CYP51 – ''Trypanosoma brucei''<br /> | ||
**[[3dam]], [[3dan]], [[3dbm]] – P45074A2 – ''Parthenium argentatum''<br /> | **[[3dam]], [[3dan]], [[3dbm]] – P45074A2 – ''Parthenium argentatum''<br /> | ||
**[[2rcm]], [[3cli]] - AtP45074A - ''Arabidopsis thaliana''<br /> | **[[2rcm]], [[3cli]] - AtP45074A - ''Arabidopsis thaliana''<br /> | ||
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**[[3e5j]], [[3e5l]] - SaP450 CYP105P1 (mutant)<br /> | **[[3e5j]], [[3e5l]] - SaP450 CYP105P1 (mutant)<br /> | ||
**[[2z3u]] - SgP450 CYP105A1 (mutant) – ''Streptomyces griseolus''<br /> | **[[2z3u]] - SgP450 CYP105A1 (mutant) – ''Streptomyces griseolus''<br /> | ||
**[[5xnt]] - P450 CYP106A2 – Bacillus butanolivorans<br /> | **[[5xnt]] - P450 CYP106A2 – ''Bacillus butanolivorans''<br /> | ||
**[[6l39]] - SrP450 CYP107G1 – Streptomyces rapamycinicus<br /> | **[[6l39]] - SrP450 CYP107G1 – ''Streptomyces rapamycinicus''<br /> | ||
**[[4wpz]] - SaP450 CYP107W1 <br /> | **[[4wpz]] - SaP450 CYP107W1 <br /> | ||
**[[2whw]], [[2wi9]], [[2vz7]] – SvP450107L1 (mutant) – ''Streptomyces venezuelae''<br /> | **[[2whw]], [[2wi9]], [[2vz7]] – SvP450107L1 (mutant) – ''Streptomyces venezuelae''<br /> | ||
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**[[4rm4]] - BsP450 CYP109B1<br /> | **[[4rm4]] - BsP450 CYP109B1<br /> | ||
**[[2jjn]], [[2jjo]] - SeP450 CYP113A1 (mutant) - ''Saccharopolyspora erythraea''<br /> | **[[2jjn]], [[2jjo]] - SeP450 CYP113A1 (mutant) - ''Saccharopolyspora erythraea''<br /> | ||
**[[6ro8]] - P450 CYP116B5 – Acinetobacter radioresistens<br /> | **[[6ro8]] - P450 CYP116B5 – ''Acinetobacter radioresistens''<br /> | ||
**[[1io8]], [[5bv5]] – SsP450 CYP119 (mutant) – ''Sulfolobus solfataricus''<br /> | **[[1io8]], [[5bv5]] – SsP450 CYP119 (mutant) – ''Sulfolobus solfataricus''<br /> | ||
**[[1io9]], [[1io7]], [[1f4u]] - SsP450 CYP119<br /> | **[[1io9]], [[1io7]], [[1f4u]] - SsP450 CYP119<br /> | ||
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**[[6hqg]] - P450 CYP153 – ''Phenylobacterium zucineum''<br /> | **[[6hqg]] - P450 CYP153 – ''Phenylobacterium zucineum''<br /> | ||
**[[6hqd]] – PsP450 CYP153 <br /> | **[[6hqd]] – PsP450 CYP153 <br /> | ||
**[[7ant]] – PoP450 CYP153 - Polaromonas<br /> | **[[7ant]] – PoP450 CYP153 - ''Polaromonas''<br /> | ||
**[[1gwi]] - ScP450 CYP154C1<br /> | **[[1gwi]] - ScP450 CYP154C1<br /> | ||
**[[6a7i]] - SvP450 CYP154C4 – Streptomyces violaceruber<br /> | **[[6a7i]] - SvP450 CYP154C4 – Streptomyces violaceruber<br /> | ||
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**[[5hiw]] - ScP450 CYP260B1 <br /> | **[[5hiw]] - ScP450 CYP260B1 <br /> | ||
**[[6gk5]] - ScP450 CYP267B1 <br /> | **[[6gk5]] - ScP450 CYP267B1 <br /> | ||
**[[6g71]] - P450 CYP1232A24 - Arthrobacter<br /> | **[[6g71]] - P450 CYP1232A24 - ''Arthrobacter<''br /> | ||
**[[6m4q]] - SspP450 – Streptomyces spectabilis<br /> | **[[6m4q]] - SspP450 – ''Streptomyces spectabilis''<br /> | ||
**[[6j82]] - SbP450 TleB – Streptomyces blastmyceticus<br /> | **[[6j82]] - SbP450 TleB – ''Streptomyces blastmyceticus''<br /> | ||
**[[7ayx]] - P450 AryC – Streptomyces filamentosus<br /> | **[[7ayx]] - P450 AryC – ''Streptomyces filamentosus''<br /> | ||
**[[7oq6]] - P450 Sas16 – Streptomyces calvus<br /> | **[[7oq6]] - P450 Sas16 –'' Streptomyces calvus''<br /> | ||
**[[6kbh]] – ReP450 – ''Rhodococcus erythropolis''<br /> | **[[6kbh]] – ReP450 – ''Rhodococcus erythropolis''<br /> | ||
**[[7v40]] – RcP450 – ''Rhodococcus coprophilus''<br /> | **[[7v40]] – RcP450 – ''Rhodococcus coprophilus''<br /> | ||
**[[6zhz]] - SanP450 – Streptomyces antibioticus<br /> | **[[6zhz]] - SanP450 – ''Streptomyces antibioticus''<br /> | ||
**[[7qan]] - P450 – Micromonospora maris<br /> | **[[7qan]] - P450 – ''Micromonospora maris"<br /> | ||
*Other CYPs complexes | *Other CYPs complexes | ||
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**[[3dsj]] - AtP450 CYP74A (mutant)+13(S)-HOD<br /> | **[[3dsj]] - AtP450 CYP74A (mutant)+13(S)-HOD<br /> | ||
**[[2rcl]] - AtP450 CYP74A+vernolic acid<br /> | **[[2rcl]] - AtP450 CYP74A+vernolic acid<br /> | ||
**[[7p6l]] - P450 CYP505A30 + dodecanoic acid – Mycelyophthora thermophila | **[[7p6l]] - P450 CYP505A30 + dodecanoic acid – ''Mycelyophthora thermophila"<br /> | ||
**[[6a15]] - AtP450 CYP90B1 (mutant) + cholesterol<br /> | **[[6a15]] - AtP450 CYP90B1 (mutant) + cholesterol<br /> | ||
**[[6a16]] - AtP450 CYP90B1 (mutant) + uniconazole<br /> | **[[6a16]] - AtP450 CYP90B1 (mutant) + uniconazole<br /> | ||
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**[[4tt5]], [[4tuv]], [[4wpd]], [[4wqj]] - P450 CYP119+ imidazole derivative – ''Sulfolobus acidocaldarius''<br /> | **[[4tt5]], [[4tuv]], [[4wpd]], [[4wqj]] - P450 CYP119+ imidazole derivative – ''Sulfolobus acidocaldarius''<br /> | ||
**[[7smz]] – MmP450 CYP142A3 + cholestenone<br /> | **[[7smz]] – MmP450 CYP142A3 + cholestenone<br /> | ||
**[[5yhj]] - P450 CYP152N1 + myristic acid - Exiguobacterium<br /> | **[[5yhj]] - P450 CYP152N1 + myristic acid - ''Exiguobacterium''<br /> | ||
**[[5fyg]] - MhP450 CYP153A + dodecanoic acid<br /> | **[[5fyg]] - MhP450 CYP153A + dodecanoic acid<br /> | ||
**[[7ao7]] – PoP450 CYP153 + octanol <br /> | **[[7ao7]] – PoP450 CYP153 + octanol <br /> | ||
**[[6to2]] - NfP450 CYP154C4 + androstan derivative – Nocardia farcinica <br /> | **[[6to2]] - NfP450 CYP154C4 + androstan derivative – ''Nocardia farcinica'' <br /> | ||
**[[4j6b]], [[4jbc]], [[4jbd]], [[4jbt]] - NfP450 CYP154C5 + hormone<br /> | **[[4j6b]], [[4jbc]], [[4jbd]], [[4jbt]] - NfP450 CYP154C5 + hormone<br /> | ||
**[[6a7j]] - SvP450 CYP154C4 + testosterone <br /> | **[[6a7j]] - SvP450 CYP154C4 + testosterone <br /> | ||