4lr6: Difference between revisions

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 ==Structure of BRD4 bromodomain 1 with a 3-methyl-4-phenylisoxazol-5-amine fragment==
-<StructureSection load='4lr6' size='340' side='right' caption='[[4lr6]], [[Resolution|resolution]] 1.29&Aring;' scene=''>
+<StructureSection load='4lr6' size='340' side='right'caption='[[4lr6]], [[Resolution|resolution]] 1.29&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[4lr6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LR6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4LR6 FirstGlance]. <br>
+<table><tr><td colspan='2'>[[4lr6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LR6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4LR6 FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1XA:3-METHYL-4-PHENYL-1,2-OXAZOL-5-AMINE'>1XA</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene></td></tr>
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1XA:3-METHYL-4-PHENYL-1,2-OXAZOL-5-AMINE'>1XA</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene></td></tr>
-<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4lrg|4lrg]]</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4lr6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lr6 OCA], [https://pdbe.org/4lr6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4lr6 RCSB], [https://www.ebi.ac.uk/pdbsum/4lr6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4lr6 ProSAT]</span></td></tr>
-<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BRD4, BRD4_HUMAN, HUNK1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4lr6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lr6 OCA], [http://pdbe.org/4lr6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4lr6 RCSB], [http://www.ebi.ac.uk/pdbsum/4lr6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4lr6 ProSAT]</span></td></tr>
 </table>
 == Disease ==
-[[http://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN]] Note=A chromosomal aberration involving BRD4 is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. Translocation t(15;19)(q14;p13) with NUT which produces a BRD4-NUT fusion protein.<ref>PMID:12543779</ref> <ref>PMID:11733348</ref>
+[https://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN] Note=A chromosomal aberration involving BRD4 is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. Translocation t(15;19)(q14;p13) with NUT which produces a BRD4-NUT fusion protein.<ref>PMID:12543779</ref> <ref>PMID:11733348</ref>
 == Function ==
-[[http://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN]] Plays a role in a process governing chromosomal dynamics during mitosis (By similarity).
+[https://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN] Plays a role in a process governing chromosomal dynamics during mitosis (By similarity).
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
@@ Line 22: / Line 20: @@
 </div>
 <div class="pdbe-citations 4lr6" style="background-color:#fffaf0;"></div>
+==See Also==
+*[[Bromodomain-containing protein 3D structures|Bromodomain-containing protein 3D structures]]
 == References ==
 <references/>
 __TOC__
 </StructureSection>
-[[Category: Human]]
+[[Category: Homo sapiens]]
-[[Category: Albrecht, B]]
+[[Category: Large Structures]]
-[[Category: Audia, J]]
+[[Category: Albrecht B]]
-[[Category: Bellon, S]]
+[[Category: Audia J]]
-[[Category: Bergeron, L]]
+[[Category: Bellon S]]
-[[Category: Birudukota, S]]
+[[Category: Bergeron L]]
-[[Category: Bryant, B]]
+[[Category: Birudukota S]]
-[[Category: Cote, A]]
+[[Category: Bryant B]]
-[[Category: Gehling, V]]
+[[Category: Cote A]]
-[[Category: Harmange, J C]]
+[[Category: Gehling V]]
-[[Category: Hewitt, M]]
+[[Category: Harmange J-C]]
-[[Category: Jayaram, H]]
+[[Category: Hewitt M]]
-[[Category: Joshi, S]]
+[[Category: Jayaram H]]
-[[Category: Leblanc, Y]]
+[[Category: Joshi S]]
-[[Category: Mertz, J]]
+[[Category: Leblanc Y]]
-[[Category: Nandana, B S]]
+[[Category: Mertz J]]
-[[Category: Nasveschuk, C]]
+[[Category: Nandana BS]]
-[[Category: Pardo, E]]
+[[Category: Nasveschuk C]]
-[[Category: Poy, F]]
+[[Category: Pardo E]]
-[[Category: Ravichandran, S]]
+[[Category: Poy F]]
-[[Category: Sandy, P]]
+[[Category: Ravichandran S]]
-[[Category: Sims, R]]
+[[Category: Sandy P]]
-[[Category: Taylor, A]]
+[[Category: Sims R]]
-[[Category: Vaswani, R]]
+[[Category: Taylor A]]
-[[Category: Yellapuntala, S]]
+[[Category: Vaswani R]]
-[[Category: Bet inhibitor]]
+[[Category: Yellapuntala S]]
-[[Category: Brd4 first bromodomain]]
-[[Category: Transcription regulator-inhibitor complex]]