4lmj: Difference between revisions

No edit summary
No edit summary
Line 1: Line 1:


==GLIC Liganded-closed-channel Conformation, Mutant T25'A==
==GLIC Liganded-closed-channel Conformation, Mutant T25'A==
<StructureSection load='4lmj' size='340' side='right' caption='[[4lmj]], [[Resolution|resolution]] 3.44&Aring;' scene=''>
<StructureSection load='4lmj' size='340' side='right'caption='[[4lmj]], [[Resolution|resolution]] 3.44&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4lmj]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Glovo Glovo]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LMJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4LMJ FirstGlance]. <br>
<table><tr><td colspan='2'>[[4lmj]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Gloeobacter_violaceus Gloeobacter violaceus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LMJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4LMJ FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=LMT:DODECYL-BETA-D-MALTOSIDE'>LMT</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=LMT:DODECYL-BETA-D-MALTOSIDE'>LMT</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4lmk|4lmk]], [[4lml|4lml]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4lmj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lmj OCA], [https://pdbe.org/4lmj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4lmj RCSB], [https://www.ebi.ac.uk/pdbsum/4lmj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4lmj ProSAT]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">glvI, glr4197 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=33072 GLOVO])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4lmj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lmj OCA], [http://pdbe.org/4lmj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4lmj RCSB], [http://www.ebi.ac.uk/pdbsum/4lmj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4lmj ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/GLIC_GLOVI GLIC_GLOVI]] Cationic channel with similar permeabilities for Na(+) and K(+), that is activated by an increase of the proton concentration on the extracellular side. Displays no permeability for chloride ions. Shows slow kinetics of activation, no desensitization and a single channel conductance of 8 pS. Might contribute to adaptation to external pH change.<ref>PMID:17167423</ref>
[https://www.uniprot.org/uniprot/GLIC_GLOVI GLIC_GLOVI] Cationic channel with similar permeabilities for Na(+) and K(+), that is activated by an increase of the proton concentration on the extracellular side. Displays no permeability for chloride ions. Shows slow kinetics of activation, no desensitization and a single channel conductance of 8 pS. Might contribute to adaptation to external pH change.<ref>PMID:17167423</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 22: Line 20:


==See Also==
==See Also==
*[[Ion channels|Ion channels]]
*[[Ion channels 3D structures|Ion channels 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Glovo]]
[[Category: Gloeobacter violaceus]]
[[Category: Gonzalez-Gutierrez, G]]
[[Category: Large Structures]]
[[Category: Grosman, C]]
[[Category: Gonzalez-Gutierrez G]]
[[Category: Membrane protein]]
[[Category: Grosman C]]
[[Category: Pentameric ligand-gated ion channel]]
[[Category: Prokaryotic cys-loop receptor]]
[[Category: Transport protein]]

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA