4lf3: Difference between revisions

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 ==Inhibitory Mechanism of an Allosteric Antibody Targeting the Glucagon Receptor==
-<StructureSection load='4lf3' size='340' side='right' caption='[[4lf3]], [[Resolution|resolution]] 2.73&Aring;' scene=''>
+<StructureSection load='4lf3' size='340' side='right'caption='[[4lf3]], [[Resolution|resolution]] 2.73&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[4lf3]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human] and [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LF3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4LF3 FirstGlance]. <br>
+<table><tr><td colspan='2'>[[4lf3]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LF3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4LF3 FirstGlance]. <br>
-</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4ers|4ers]], [[4lex|4lex]]</td></tr>
+</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4lf3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lf3 OCA], [https://pdbe.org/4lf3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4lf3 RCSB], [https://www.ebi.ac.uk/pdbsum/4lf3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4lf3 ProSAT]</span></td></tr>
-<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Anti GCGR mAb ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice]), GCGR ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4lf3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lf3 OCA], [http://pdbe.org/4lf3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4lf3 RCSB], [http://www.ebi.ac.uk/pdbsum/4lf3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4lf3 ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/GLR_HUMAN GLR_HUMAN]] This is a receptor for glucagon which plays a central role in regulating the level of blood glucose by controlling the rate of hepatic glucose production and insulin secretion. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system.
+[https://www.uniprot.org/uniprot/GLR_HUMAN GLR_HUMAN] This is a receptor for glucagon which plays a central role in regulating the level of blood glucose by controlling the rate of hepatic glucose production and insulin secretion. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system.
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
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 </div>
 <div class="pdbe-citations 4lf3" style="background-color:#fffaf0;"></div>
+==See Also==
+*[[Glucagon receptor|Glucagon receptor]]
 == References ==
 <references/>
 __TOC__
 </StructureSection>
-[[Category: Human]]
+[[Category: Homo sapiens]]
-[[Category: Lk3 transgenic mice]]
+[[Category: Large Structures]]
-[[Category: Mukund, S]]
+[[Category: Mus musculus]]
-[[Category: Murray, J M]]
+[[Category: Mukund S]]
-[[Category: Fab fragment]]
+[[Category: Murray JM]]
-[[Category: Gcgr]]
-[[Category: Immune system]]