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==Human Methyltransferase-Like Protein 21A==
==Human Methyltransferase-Like Protein 21A==
<StructureSection load='4lec' size='340' side='right' caption='[[4lec]], [[Resolution|resolution]] 2.28&Aring;' scene=''>
<StructureSection load='4lec' size='340' side='right'caption='[[4lec]], [[Resolution|resolution]] 2.28&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4lec]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LEC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4LEC FirstGlance]. <br>
<table><tr><td colspan='2'>[[4lec]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LEC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4LEC FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">METTL21A, FAM119A, HCA557B ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4lec FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lec OCA], [https://pdbe.org/4lec PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4lec RCSB], [https://www.ebi.ac.uk/pdbsum/4lec PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4lec ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4lec FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lec OCA], [http://pdbe.org/4lec PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4lec RCSB], [http://www.ebi.ac.uk/pdbsum/4lec PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4lec ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/MT21A_HUMAN MT21A_HUMAN]] Protein-lysine methyltransferase.<ref>PMID:22948820</ref>
[https://www.uniprot.org/uniprot/MT21A_HUMAN MT21A_HUMAN] Protein-lysine methyltransferase.<ref>PMID:22948820</ref>  
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Arrowsmith, C H]]
[[Category: Large Structures]]
[[Category: Bountra, C]]
[[Category: Arrowsmith CH]]
[[Category: Brown, P J]]
[[Category: Bountra C]]
[[Category: Dong, A]]
[[Category: Brown PJ]]
[[Category: Edwards, A M]]
[[Category: Dong A]]
[[Category: Fenner, M]]
[[Category: Edwards AM]]
[[Category: Structural genomic]]
[[Category: Fenner M]]
[[Category: Wernimont, A]]
[[Category: Wernimont A]]
[[Category: Wu, H]]
[[Category: Wu H]]
[[Category: Zeng, H]]
[[Category: Zeng H]]
[[Category: Methyltransferase]]
[[Category: Methyltransferase-like protein 21a]]
[[Category: Mettl21a]]
[[Category: Sgc]]
[[Category: Transferase]]

Revision as of 13:55, 14 December 2022

Human Methyltransferase-Like Protein 21AHuman Methyltransferase-Like Protein 21A

Structural highlights

4lec is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

MT21A_HUMAN Protein-lysine methyltransferase.[1]

References

  1. ↑ Kernstock S, Davydova E, Jakobsson M, Moen A, Pettersen S, Maelandsmo GM, Egge-Jacobsen W, Falnes PO. Lysine methylation of VCP by a member of a novel human protein methyltransferase family. Nat Commun. 2012;3:1038. doi: 10.1038/ncomms2041. PMID:22948820 doi:10.1038/ncomms2041

4lec, resolution 2.28Å

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