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==Cryo-EM structure of GMPCPP-microtubules in complex with VASH2-SVBP== | |||
<StructureSection load='7zcw' size='340' side='right'caption='[[7zcw]], [[Resolution|resolution]] 3.60Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[7zcw]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7ZCW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7ZCW FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=G2P:PHOSPHOMETHYLPHOSPHONIC+ACID+GUANYLATE+ESTER'>G2P</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7zcw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7zcw OCA], [https://pdbe.org/7zcw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7zcw RCSB], [https://www.ebi.ac.uk/pdbsum/7zcw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7zcw ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/TBA1B_HUMAN TBA1B_HUMAN] Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Blum T]] | |||
[[Category: Choi SR]] | |||
[[Category: Steinmetz MO]] | |||
Revision as of 13:06, 14 December 2022
Cryo-EM structure of GMPCPP-microtubules in complex with VASH2-SVBPCryo-EM structure of GMPCPP-microtubules in complex with VASH2-SVBP
Structural highlights
FunctionTBA1B_HUMAN Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. |
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