Fatty acid synthesis: Difference between revisions
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Straight-chain fatty acid synthesis occurs via the six recurring reactions shown below, until the 16-carbon <scene name='92/928693/Cv/2'>palmitic acid</scene> is produced. The fatty acids are synthesized in microorganisms and list the enzymes found in ''Escherichia coli''. Fatty acid synthesis is performed by fatty acid synthase II (FASII), which in general contain multiple enzymes that act as one complex. FASII is present in prokaryotes, plants, fungi, and parasites, as well as in mitochondria. | Straight-chain fatty acid synthesis occurs via the six recurring reactions shown below, until the 16-carbon <scene name='92/928693/Cv/2'>palmitic acid</scene> is produced. The fatty acids are synthesized in microorganisms and list the enzymes found in ''Escherichia coli''. Fatty acid synthesis is performed by fatty acid synthase II (FASII), which in general contain multiple enzymes that act as one complex. FASII is present in prokaryotes, plants, fungi, and parasites, as well as in mitochondria. | ||
Most of the acetyl-CoA which is converted into fatty acids is derived from carbohydrates via the glycolytic pathway. | Most of the acetyl-CoA which is converted into fatty acids is derived from carbohydrates via the [[glycolytic pathway]]. '''Pyruvate decarboxylation or pyruvate oxidation''', also known as the link reaction (or oxidative decarboxylation of pyruvate), is the conversion of <scene name='39/392339/Cv1/11'>pyruvate</scene> into <scene name='43/430893/Cv/2'>Acetyl-CoA</scene> by the enzyme complex pyruvate dehydrogenase complex (see [[Pyruvate dehydrogenase]]). | ||
''Step 1 Acetyl-CoA:ACP transacylase; (acyl-carrier-protein) S-acetyltransferase; EC 2.3.1.38'' | ''Step 1 Acetyl-CoA:ACP transacylase; (acyl-carrier-protein) S-acetyltransferase; EC 2.3.1.38'' | ||