4l59: Difference between revisions
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==Crystal structure of the 3-MBT repeat domain of L3MBTL3 and UNC2533 complex== | ==Crystal structure of the 3-MBT repeat domain of L3MBTL3 and UNC2533 complex== | ||
<StructureSection load='4l59' size='340' side='right' caption='[[4l59]], [[Resolution|resolution]] 2.29Å' scene=''> | <StructureSection load='4l59' size='340' side='right'caption='[[4l59]], [[Resolution|resolution]] 2.29Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4l59]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[4l59]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4L59 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4L59 FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1VZ:4-(PYRROLIDIN-1-YL)-1-{4-[2-(PYRROLIDIN-1-YL)ETHYL]PHENYL}PIPERIDINE'>1VZ</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1VZ:4-(PYRROLIDIN-1-YL)-1-{4-[2-(PYRROLIDIN-1-YL)ETHYL]PHENYL}PIPERIDINE'>1VZ</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4l59 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4l59 OCA], [https://pdbe.org/4l59 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4l59 RCSB], [https://www.ebi.ac.uk/pdbsum/4l59 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4l59 ProSAT]</span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/LMBL3_HUMAN LMBL3_HUMAN] Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Required for normal maturation of myeloid progenitor cells (By similarity). | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Arrowsmith | [[Category: Large Structures]] | ||
[[Category: Baughman | [[Category: Arrowsmith CH]] | ||
[[Category: Bountra | [[Category: Baughman BM]] | ||
[[Category: Brown | [[Category: Bountra C]] | ||
[[Category: Camerino | [[Category: Brown PJ]] | ||
[[Category: Dickson | [[Category: Camerino MA]] | ||
[[Category: Dong | [[Category: Dickson BM]] | ||
[[Category: Edwards | [[Category: Dong A]] | ||
[[Category: Frye | [[Category: Edwards AM]] | ||
[[Category: Graslund | [[Category: Frye SV]] | ||
[[Category: James | [[Category: Graslund S]] | ||
[[Category: Janzen | [[Category: James LI]] | ||
[[Category: Kireev | [[Category: Janzen WP]] | ||
[[Category: Norris | [[Category: Kireev DB]] | ||
[[Category: Ravichandran | [[Category: Norris JL]] | ||
[[Category: Ravichandran M]] | |||
[[Category: Zhong | [[Category: Zhong N]] | ||