4l3i: Difference between revisions

<StructureSection load='4l3i' size='340' side='right'caption='[[4l3i]], [[Resolution|resolution]] 3.60&Aring;' scene=''>

<table><tr><td colspan='2'>[[4l3i]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4L3I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4L3I FirstGlance]. <br>

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4l3i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4l3i OCA], [https://pdbe.org/4l3i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4l3i RCSB], [https://www.ebi.ac.uk/pdbsum/4l3i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4l3i ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/PRC1_HUMAN PRC1_HUMAN] Key regulator of cytokinesis that cross-links antiparrallel microtubules at an average distance of 35 nM. Essential for controlling the spatiotemporal formation of the midzone and successful cytokinesis. Required for KIF14 localization to the central spindle and midbody. Required to recruit PLK1 to the spindle. Stimulates PLK1 phosphorylation of RACGAP1 to allow recruitment of ECT2 to the central spindle.<ref>PMID:9885575</ref> <ref>PMID:12082078</ref> <ref>PMID:15297875</ref> <ref>PMID:15625105</ref> <ref>PMID:16431929</ref> <ref>PMID:19468300</ref> <ref>PMID:20691902</ref>  

[[Category: Homo sapiens]]

[[Category: Large Structures]]

[[Category: Darst SA]]

[[Category: Kapoor TM]]

[[Category: Subramanian R]]

[[Category: Tan L]]

[[Category: Ti S]]