7zo8: Difference between revisions

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'''Unreleased structure'''


The entry 7zo8 is ON HOLD  until Paper Publication
==cryo-EM structure of CGT ABC transporter in nanodisc apo state==
 
<StructureSection load='7zo8' size='340' side='right'caption='[[7zo8]], [[Resolution|resolution]] 3.60&Aring;' scene=''>
Authors: Jaroslaw, S., Dong, C.N., Frank, L., Na, W., Renato, Z., Seunho, J., Henning, S., Christoph, D.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[7zo8]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Brucella_abortus_2308 Brucella abortus 2308]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7ZO8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7ZO8 FirstGlance]. <br>
Description: cryo-EM structure of CGT ABC transporter in nanodisc apo state
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PLC:DIUNDECYL+PHOSPHATIDYL+CHOLINE'>PLC</scene></td></tr>
[[Category: Unreleased Structures]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7zo8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7zo8 OCA], [https://pdbe.org/7zo8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7zo8 RCSB], [https://www.ebi.ac.uk/pdbsum/7zo8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7zo8 ProSAT]</span></td></tr>
[[Category: Dong, C.N]]
</table>
[[Category: Seunho, J]]
== Function ==
[[Category: Renato, Z]]
[https://www.uniprot.org/uniprot/NDVA_BRUA2 NDVA_BRUA2] Involved in beta-(1-->2)glucan export. Its export to the periplasmic space is required to exert its action as a virulence factor. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (Probable).<ref>PMID:15039351</ref>
[[Category: Jaroslaw, S]]
== References ==
[[Category: Na, W]]
<references/>
[[Category: Frank, L]]
__TOC__
[[Category: Christoph, D]]
</StructureSection>
[[Category: Henning, S]]
[[Category: Brucella abortus 2308]]
[[Category: Large Structures]]
[[Category: Christoph D]]
[[Category: Dong CN]]
[[Category: Frank L]]
[[Category: Henning S]]
[[Category: Jaroslaw S]]
[[Category: Na W]]
[[Category: Renato Z]]
[[Category: Seunho J]]

Revision as of 11:17, 7 December 2022

cryo-EM structure of CGT ABC transporter in nanodisc apo statecryo-EM structure of CGT ABC transporter in nanodisc apo state

Structural highlights

7zo8 is a 2 chain structure with sequence from Brucella abortus 2308. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

NDVA_BRUA2 Involved in beta-(1-->2)glucan export. Its export to the periplasmic space is required to exert its action as a virulence factor. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (Probable).[1]

References

  1. ↑ Roset MS, Ciocchini AE, Ugalde RA, Inon de Iannino N. Molecular cloning and characterization of cgt, the Brucella abortus cyclic beta-1,2-glucan transporter gene, and its role in virulence. Infect Immun. 2004 Apr;72(4):2263-71. PMID:15039351

7zo8, resolution 3.60Å

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OCA
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