Cytochrome bd oxidase: Difference between revisions
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Since cytochrome ''bd'' oxidases are only found in prokaryotes and are required for [https://en.wikipedia.org/wiki/Infection#Bacterial_or_viral pathogenic bacterial infections], inhibitors that target cytochrome ''bd'' oxidase are promising [https://en.wikipedia.org/wiki/Antibiotic antibacterial] agents. Compounds that target heme b<sub>558</sub><ref name="Harikishore">PMID: 31939065</ref>, create [https://en.wikipedia.org/wiki/Allotropes_of_oxygen unusable forms of oxygen]<ref name="Galván">PMID: 30790617</ref>, and target the o-channel <ref name="Lu">PMID: 26015371 </ref> have shown potential in halting bacterial growth. | Since cytochrome ''bd'' oxidases are only found in prokaryotes and are required for [https://en.wikipedia.org/wiki/Infection#Bacterial_or_viral pathogenic bacterial infections], inhibitors that target cytochrome ''bd'' oxidase are promising [https://en.wikipedia.org/wiki/Antibiotic antibacterial] agents. Compounds that target heme b<sub>558</sub><ref name="Harikishore">PMID: 31939065</ref>, create [https://en.wikipedia.org/wiki/Allotropes_of_oxygen unusable forms of oxygen]<ref name="Galván">PMID: 30790617</ref>, and target the o-channel <ref name="Lu">PMID: 26015371 </ref> have shown potential in halting bacterial growth. | ||
== 3D Structures of cytochrome bd oxidase == | == 3D Structures of cytochrome bd oxidase == | ||
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[[5doq]], [[5ir6]] - Cytbd subunits 1,2 + protein - ''Geobacillus thermodenitrificans''<br /> | [[5doq]], [[5ir6]] - Cytbd subunits 1,2 + protein - ''Geobacillus thermodenitrificans''<br /> | ||
[[7d5i]], [[7nkz]] - Cytbd – ''Mycobacterium tuberculosis'' - Cryo EM<br /> | [[7d5i]], [[7nkz]] - Cytbd – ''Mycobacterium tuberculosis'' - Cryo EM<br /> | ||
</StructureSection> | |||
== References == | == References == | ||
<references/> | <references/> | ||
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Marissa Villarreal | Marissa Villarreal | ||
[[Category:Topic Page]] | |||