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<StructureSection load='4ken' size='340' side='right'caption='[[4ken]], [[Resolution|resolution]] 1.89&Aring;' scene=''>
<StructureSection load='4ken' size='340' side='right'caption='[[4ken]], [[Resolution|resolution]] 1.89&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4ken]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KEN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4KEN FirstGlance]. <br>
<table><tr><td colspan='2'>[[4ken]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KEN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4KEN FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1S7:(2R)-2-{(1S)-1-METHOXY-2-OXO-1-[(THIOPHEN-2-YLACETYL)AMINO]ETHYL}-5-METHYLIDENE-5,6-DIHYDRO-2H-1,3-THIAZINE-4-CARBOXYLIC+ACID'>1S7</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1S7:(2R)-2-{(1S)-1-METHOXY-2-OXO-1-[(THIOPHEN-2-YLACETYL)AMINO]ETHYL}-5-METHYLIDENE-5,6-DIHYDRO-2H-1,3-THIAZINE-4-CARBOXYLIC+ACID'>1S7</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4jxg|4jxg]], [[4kg2|4kg2]], [[4kg5|4kg5]], [[4kg6|4kg6]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ken FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ken OCA], [https://pdbe.org/4ken PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ken RCSB], [https://www.ebi.ac.uk/pdbsum/4ken PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ken ProSAT]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ampC, ampA, b4150, JW4111 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ken FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ken OCA], [http://pdbe.org/4ken PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ken RCSB], [http://www.ebi.ac.uk/pdbsum/4ken PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ken ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/AMPC_ECOLI AMPC_ECOLI]] This protein is a serine beta-lactamase with a substrate specificity for cephalosporins.  
[https://www.uniprot.org/uniprot/AMPC_ECOLI AMPC_ECOLI] This protein is a serine beta-lactamase with a substrate specificity for cephalosporins.


==See Also==
==See Also==
*[[Beta-lactamase|Beta-lactamase]]
*[[Beta-lactamase 3D structures|Beta-lactamase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Beta-lactamase]]
[[Category: Escherichia coli K-12]]
[[Category: Ecoli]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Baggett, V L]]
[[Category: Baggett VL]]
[[Category: Docter, B E]]
[[Category: Docter BE]]
[[Category: Powers, R A]]
[[Category: Powers RA]]
[[Category: Wallar, B J]]
[[Category: Wallar BJ]]
[[Category: Acyl-enzyme complex]]
[[Category: Cephalosporinase]]
[[Category: Hydrolase-antibiotic complex]]
[[Category: Serine hydrolase]]

Revision as of 14:54, 30 November 2022

Crystal Structure of AmpC beta-lactamase N152G Mutant in Complex with CefoxitinCrystal Structure of AmpC beta-lactamase N152G Mutant in Complex with Cefoxitin

Structural highlights

4ken is a 1 chain structure with sequence from Escherichia coli K-12. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

AMPC_ECOLI This protein is a serine beta-lactamase with a substrate specificity for cephalosporins.

See Also

4ken, resolution 1.89Å

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