4jph: Difference between revisions
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==Crystal structure of Protein Related to DAN and Cerberus (PRDC)== | ==Crystal structure of Protein Related to DAN and Cerberus (PRDC)== | ||
<StructureSection load='4jph' size='340' side='right' caption='[[4jph]], [[Resolution|resolution]] 2.25Å' scene=''> | <StructureSection load='4jph' size='340' side='right'caption='[[4jph]], [[Resolution|resolution]] 2.25Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4jph]] is a 4 chain structure with sequence from [ | <table><tr><td colspan='2'>[[4jph]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JPH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4JPH FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=GSH:GLUTATHIONE'>GSH</scene> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=GSH:GLUTATHIONE'>GSH</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4jph FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4jph OCA], [https://pdbe.org/4jph PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4jph RCSB], [https://www.ebi.ac.uk/pdbsum/4jph PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4jph ProSAT]</span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/GREM2_MOUSE GREM2_MOUSE] Cytokine that inhibits the activity of BMP2 and BMP4 in a dose-dependent manner. Antagonized BMP4-induced suppression of progesterone production in granulosa cells.<ref>PMID:15039429</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Mus musculus]] | ||
[[Category: | [[Category: Deng X]] | ||
[[Category: | [[Category: Kattamuri C]] | ||
[[Category: | [[Category: Nolan KT]] | ||
[[Category: | [[Category: Thompson TB]] | ||