4jf2: Difference between revisions
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<StructureSection load='4jf2' size='340' side='right'caption='[[4jf2]], [[Resolution|resolution]] 2.28Å' scene=''> | <StructureSection load='4jf2' size='340' side='right'caption='[[4jf2]], [[Resolution|resolution]] 2.28Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4jf2]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JF2 OCA]. For a <b>guided tour on the structure components</b> use [ | <table><tr><td colspan='2'>[[4jf2]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lacticaseibacillus_rhamnosus Lacticaseibacillus rhamnosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JF2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4JF2 FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CS:CESIUM+ION'>CS</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PRF:7-DEAZA-7-AMINOMETHYL-GUANINE'>PRF | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CS:CESIUM+ION'>CS</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PRF:7-DEAZA-7-AMINOMETHYL-GUANINE'>PRF</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4jf2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4jf2 OCA], [https://pdbe.org/4jf2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4jf2 RCSB], [https://www.ebi.ac.uk/pdbsum/4jf2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4jf2 ProSAT]</span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Lacticaseibacillus rhamnosus]] | |||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Liberman | [[Category: Liberman JA]] | ||
[[Category: Wedekind | [[Category: Wedekind JE]] | ||
Revision as of 14:10, 24 November 2022
Structure of a class II preQ1 riboswitch reveals ligand recognition by a new foldStructure of a class II preQ1 riboswitch reveals ligand recognition by a new fold
Structural highlights
Publication Abstract from PubMedPreQ1 riboswitches regulate genes by binding the pyrrolopyrimidine intermediate preQ1 during the biosynthesis of the essential tRNA base queuosine. We report what is to our knowledge the first preQ1-II riboswitch structure at 2.3-A resolution, which uses a previously uncharacterized fold to achieve effector recognition at the confluence of a three-way helical junction flanking a pseudoknotted ribosome-binding site. The results account for translational control mediated by the preQ1-II riboswitch class and expand the known repertoire of ligand-binding modes used by regulatory RNAs. Structure of a class II preQ riboswitch reveals ligand recognition by a new fold.,Liberman JA, Salim M, Krucinska J, Wedekind JE Nat Chem Biol. 2013 Apr 14. doi: 10.1038/nchembio.1231. PMID:23584677[1] From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine. See AlsoReferences
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