1j1h: Difference between revisions

Revision as of 20:41, 2 May 2008

Solution structure of a tmRNA-binding protein, SmpB, from Thermus thermophilus

OverviewOverview

Small protein B (SmpB) is required for trans-translation, binding specifically to tmRNA. We show here the solution structure of SmpB from an extremely thermophilic bacterium, Thermus thermophilus HB8, determined by heteronuclear nuclear magnetic resonance methods. The core of the protein consists of an antiparallel beta-barrel twisted up from eight beta-strands, each end of which is capped with the second or third helix, and the first helix is located beside the barrel. Its C-terminal sequence (20 residues), which is rich in basic residues, shows a poorly structured form, as often seen in isolated ribosomal proteins. The results are discussed in relation to the oligonucleotide binding fold.

About this StructureAbout this Structure

1J1H is a Single protein structure of sequence from Thermus thermophilus. Full crystallographic information is available from OCA.

ReferenceReference

Solution structure of a tmRNA-binding protein, SmpB, from Thermus thermophilus., Someya T, Nameki N, Hosoi H, Suzuki S, Hatanaka H, Fujii M, Terada T, Shirouzu M, Inoue Y, Shibata T, Kuramitsu S, Yokoyama S, Kawai G, FEBS Lett. 2003 Jan 30;535(1-3):94-100. PMID:12560085 Page seeded by OCA on Fri May 2 20:41:13 2008

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

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 [[Image:1j1h.gif|left|200px]]
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 '''Solution structure of a tmRNA-binding protein, SmpB, from Thermus thermophilus'''
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 [[Category: Terada, T.]]
 [[Category: Yokoyama, S.]]
-[[Category: ob fold]]
+[[Category: Ob fold]]
-[[Category: riken structural genomics/proteomics initiative]]
+[[Category: Riken structural genomics/proteomics initiative]]
-[[Category: rsgi]]
+[[Category: Rsgi]]
-[[Category: smpb]]
+[[Category: Smpb]]
-[[Category: ssra associated protein]]
+[[Category: Ssra associated protein]]
-[[Category: structural genomic]]
+[[Category: Structural genomic]]
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May  2 20:41:13 2008''
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 21:27:35 2008''