Citric Acid Cycle: Difference between revisions
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The [[Citric Acid Cycle]] (tricarboxylic acid cycle) is a series of enzyme catalyzed reactions which are critical in cellular respiration. Under oxidative conditions, pyruvate continues to be metabolized through the tricarboxylic acid cycle. In this cycle, Acetyl-CoA, a byproduct of [[glycolysis]], along with various cofactors, are broken down into carbon dioxide, water, and energy in the form of GTP and NADH. | The [[Citric Acid Cycle]] (tricarboxylic acid cycle) is a series of enzyme catalyzed reactions which are critical in cellular respiration. Under oxidative conditions, pyruvate continues to be metabolized through the tricarboxylic acid cycle. In this cycle, Acetyl-CoA, a byproduct of [[glycolysis]], along with various cofactors, are broken down into carbon dioxide, water, and energy in the form of GTP and NADH. | ||
'''Pyruvate decarboxylation or pyruvate oxidation''', also known as the link reaction (or oxidative decarboxylation of pyruvate), is the conversion of <scene name='39/392339/Cv/16'>pyruvate</scene> into Acetyl-CoA by the enzyme complex pyruvate dehydrogenase complex (see [[Pyruvate dehydrogenase]]). | '''Pyruvate decarboxylation or pyruvate oxidation''', also known as the link reaction (or oxidative decarboxylation of pyruvate), is the conversion of <scene name='39/392339/Cv/16'>pyruvate</scene> into <scene name='43/430893/Cv/1'>Acetyl-CoA</scene> by the enzyme complex pyruvate dehydrogenase complex (see [[Pyruvate dehydrogenase]]). | ||
The multienzyme complex together catalyzes five distinct reactions in the conversion of pyruvate to Acetyl-CoA. The overall result is described by the following reaction: | The multienzyme complex together catalyzes five distinct reactions in the conversion of pyruvate to Acetyl-CoA. The overall result is described by the following reaction: | ||