FirstGlance/Virus Capsids and Other Large Assemblies: Difference between revisions
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==Polio Virus== | ==Polio Virus== | ||
The polio (poliomyelitis) virus mostly infects children under 5, and 1/200 infections causes permanent paralysis with 5-10% of those being fatal<ref name="polio-who">[https://www.who.int/news-room/fact-sheets/detail/poliomyelitis Poliomyelitis Overview, World Health Organization].</ref>. Vaccines were developed in the 1950s. Polio is nearly eradicated worldwide, but endemic pockets persist in regions of Afghanistan and Pakistan where vaccination campaigns are most challenging. | The polio (poliomyelitis) virus mostly infects children under 5, and 1/200 infections causes permanent paralysis with 5-10% of those being fatal<ref name="polio-who">[https://www.who.int/news-room/fact-sheets/detail/poliomyelitis Poliomyelitis Overview, World Health Organization].</ref>. Vaccines were developed in the 1950s<ref name="polio-vaccines">[https://en.wikipedia.org/wiki/Polio#Vaccine Polio Vaccines at Wikipedia].</ref>. Polio is nearly eradicated worldwide, but endemic pockets persist in regions of Afghanistan and Pakistan where vaccination campaigns are most challenging<ref name="polio-eradication">[https://en.wikipedia.org/wiki/Polio#Eradication Eradication of Polio in Wikipedia].</ref>. Polio was declared eradicated from the Americas in 1994, but in 2022 a live vaccine-derived strain of polio was found circulating in parts of New York State, USA<ref name="polio-usa">[https://en.wikipedia.org/wiki/Polio#Americas Polio in the Americas, Wikipedia].</ref>. | ||
Polio virus is small (among viruses pathogenic for humans) with an RNA genome inside a single-shell protein capsid. [[1pov]] | Polio virus is small (among viruses pathogenic for humans) with an RNA genome inside a single-shell protein capsid. [[1pov]] | ||