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==Naphthalene 1,2-Dioxygenase bound to thioanisole==
==Naphthalene 1,2-Dioxygenase bound to thioanisole==
<StructureSection load='4hm8' size='340' side='right' caption='[[4hm8]], [[Resolution|resolution]] 1.30&Aring;' scene=''>
<StructureSection load='4hm8' size='340' side='right'caption='[[4hm8]], [[Resolution|resolution]] 1.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4hm8]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseu8 Pseu8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HM8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4HM8 FirstGlance]. <br>
<table><tr><td colspan='2'>[[4hm8]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_sp._C18 Pseudomonas sp. C18]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HM8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4HM8 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=16R:(METHYLSULFANYL)BENZENE'>16R</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=16R:(METHYLSULFANYL)BENZENE'>16R</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4hm0|4hm0]], [[4hm1|4hm1]], [[4hm2|4hm2]], [[4hm3|4hm3]], [[4hm4|4hm4]], [[4hm5|4hm5]], [[4hm6|4hm6]], [[4hm7|4hm7]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4hm8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hm8 OCA], [https://pdbe.org/4hm8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4hm8 RCSB], [https://www.ebi.ac.uk/pdbsum/4hm8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4hm8 ProSAT]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">doxB, NC_004999.1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=69011 PSEU8]), doxD, NC_004999.1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=69011 PSEU8])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Naphthalene_1,2-dioxygenase Naphthalene 1,2-dioxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.12.12 1.14.12.12] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4hm8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hm8 OCA], [http://pdbe.org/4hm8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4hm8 RCSB], [http://www.ebi.ac.uk/pdbsum/4hm8 PDBsum]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/NDOB_PSEU8 NDOB_PSEU8]] Component of the naphthalene dioxygenase (NDO) multicomponent enzyme system which catalyzes the incorporation of both atoms of molecular oxygen into naphthalene to form cis-naphthalene dihydrodiol. [[http://www.uniprot.org/uniprot/NDOC_PSEU8 NDOC_PSEU8]] Component of the naphthalene dioxygenase (NDO) multicomponent enzyme system which catalyzes the incorporation of both atoms of molecular oxygen into naphthalene to form cis-naphthalene dihydrodiol. The beta subunit may be responsible for the substrate specificity of the enzyme.  
[https://www.uniprot.org/uniprot/NDOB_PSEU8 NDOB_PSEU8] Component of the naphthalene dioxygenase (NDO) multicomponent enzyme system which catalyzes the incorporation of both atoms of molecular oxygen into naphthalene to form cis-naphthalene dihydrodiol.


==See Also==
==See Also==
*[[Dioxygenase|Dioxygenase]]
*[[Dioxygenase 3D structures|Dioxygenase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Naphthalene 1,2-dioxygenase]]
[[Category: Large Structures]]
[[Category: Pseu8]]
[[Category: Pseudomonas sp. C18]]
[[Category: Ferraro, D J]]
[[Category: Ferraro DJ]]
[[Category: Ramaswamy, S]]
[[Category: Ramaswamy S]]
[[Category: Oxidoreductase-oxidoreductase inhibitor complex]]

Revision as of 11:26, 3 November 2022

Naphthalene 1,2-Dioxygenase bound to thioanisoleNaphthalene 1,2-Dioxygenase bound to thioanisole

Structural highlights

4hm8 is a 2 chain structure with sequence from Pseudomonas sp. C18. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:, , , ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

NDOB_PSEU8 Component of the naphthalene dioxygenase (NDO) multicomponent enzyme system which catalyzes the incorporation of both atoms of molecular oxygen into naphthalene to form cis-naphthalene dihydrodiol.

See Also

4hm8, resolution 1.30Å

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