4hhs: Difference between revisions

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==Crystal Structure of fatty acid alpha-dioxygenase (Arabidopsis thaliana)==
==Crystal Structure of fatty acid alpha-dioxygenase (Arabidopsis thaliana)==
<StructureSection load='4hhs' size='340' side='right' caption='[[4hhs]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
<StructureSection load='4hhs' size='340' side='right'caption='[[4hhs]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4hhs]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Arath Arath]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HHS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4HHS FirstGlance]. <br>
<table><tr><td colspan='2'>[[4hhs]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HHS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4HHS FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BNG:B-NONYLGLUCOSIDE'>BNG</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=P6G:HEXAETHYLENE+GLYCOL'>P6G</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BNG:B-NONYLGLUCOSIDE'>BNG</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=P6G:HEXAETHYLENE+GLYCOL'>P6G</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4hhr|4hhr]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4hhs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hhs OCA], [https://pdbe.org/4hhs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4hhs RCSB], [https://www.ebi.ac.uk/pdbsum/4hhs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4hhs ProSAT]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">T13O15.6, alphaDOX1, At3g01420/T13O15.6, DOX1, At3g01420, AT3G01420 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3702 ARATH])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4hhs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hhs OCA], [http://pdbe.org/4hhs PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4hhs RCSB], [http://www.ebi.ac.uk/pdbsum/4hhs PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4hhs ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/DOX1_ARATH DOX1_ARATH]] Alpha-dioxygenase that catalyzes the primary oxygenation of fatty acids into oxylipins. Mediates a protection against oxidative stress and cell death, probably by generating some lipid-derived molecules. Promotes local and systemic plant defense in a salicylic acid (SA)-dependent manner, including the establishment of systemic acquired resistance (SAR) in response to incompatible interaction. Involved in a negative regulation of abscisic acid (ABA)-mediated signaling pathway.<ref>PMID:12060227</ref> <ref>PMID:10455113</ref> <ref>PMID:22199234</ref>
[https://www.uniprot.org/uniprot/DOX1_ARATH DOX1_ARATH] Alpha-dioxygenase that catalyzes the primary oxygenation of fatty acids into oxylipins. Mediates a protection against oxidative stress and cell death, probably by generating some lipid-derived molecules. Promotes local and systemic plant defense in a salicylic acid (SA)-dependent manner, including the establishment of systemic acquired resistance (SAR) in response to incompatible interaction. Involved in a negative regulation of abscisic acid (ABA)-mediated signaling pathway.<ref>PMID:12060227</ref> <ref>PMID:10455113</ref> <ref>PMID:22199234</ref>  
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== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Arath]]
[[Category: Arabidopsis thaliana]]
[[Category: Goulah, C C]]
[[Category: Large Structures]]
[[Category: Koszelak-Rosenblum, M]]
[[Category: Goulah CC]]
[[Category: Malkowski, M G]]
[[Category: Koszelak-Rosenblum M]]
[[Category: Zhu, G]]
[[Category: Malkowski MG]]
[[Category: Calcium binding]]
[[Category: Zhu G]]
[[Category: Cyclooxygenase myeloperoxidase folding]]
[[Category: Fatty acid dioxygenase]]
[[Category: Monotopic membrane protein]]
[[Category: Oxidoreductase]]

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