7wtt: Difference between revisions

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-'''Unreleased structure'''
-The entry 7wtt is ON HOLD  until Paper Publication
+==Cryo-EM structure of a human pre-40S ribosomal subunit - State RRP12-A1 (with CK1)==
+<StructureSection load='7wtt' size='340' side='right'caption='[[7wtt]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
-Authors: Cheng, J., Lau, B., Thoms, M., Ameismeier, M., Berninghausen, O., Hurt, E., Beckmann, R.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[7wtt]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7WTT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7WTT FirstGlance]. <br>
-Description: Cryo-EM structure of a human pre-40S ribosomal subunit -State RRP12-A1 (with CK1)
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=G7M:N7-METHYL-GUANOSINE-5-MONOPHOSPHATE'>G7M</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7wtt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7wtt OCA], [https://pdbe.org/7wtt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7wtt RCSB], [https://www.ebi.ac.uk/pdbsum/7wtt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7wtt ProSAT]</span></td></tr>
-[[Category: Cheng, J]]
+</table>
-[[Category: Hurt, E]]
+== Disease ==
-[[Category: Berninghausen, O]]
+[https://www.uniprot.org/uniprot/RS17_HUMAN RS17_HUMAN] Blackfan-Diamond disease. Diamond-Blackfan anemia 4 (DBA4) [MIM:[https://omim.org/entry/612527 612527]: A form of Diamond-Blackfan anemia, a congenital non-regenerative hypoplastic anemia that usually presents early in infancy. Diamond-Blackfan anemia is characterized by a moderate to severe macrocytic anemia, erythroblastopenia, and an increased risk of developing leukemia. 30 to 40% of Diamond-Blackfan anemia patients present with short stature and congenital anomalies, the most frequent being craniofacial (Pierre-Robin syndrome and cleft palate), thumb and urogenital anomalies. Note=The disease is caused by mutations affecting the gene represented in this entry.<ref>PMID:17647292</ref> <ref>PMID:19061985</ref>
-[[Category: Lau, B]]
+== Function ==
-[[Category: Ameismeier, M]]
+[https://www.uniprot.org/uniprot/RS17_HUMAN RS17_HUMAN]
-[[Category: Beckmann, R]]
+== References ==
-[[Category: Thoms, M]]
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Homo sapiens]]
+[[Category: Large Structures]]
+[[Category: Ameismeier M]]
+[[Category: Beckmann R]]
+[[Category: Berninghausen O]]
+[[Category: Cheng J]]
+[[Category: Hurt E]]
+[[Category: Lau B]]
+[[Category: Thoms M]]