1ia4: Difference between revisions
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<StructureSection load='1ia4' size='340' side='right'caption='[[1ia4]], [[Resolution|resolution]] 1.85Å' scene=''> | <StructureSection load='1ia4' size='340' side='right'caption='[[1ia4]], [[Resolution|resolution]] 1.85Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1ia4]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[1ia4]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Candida_albicans Candida albicans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IA4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1IA4 FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene>, <scene name='pdbligand=TQ6:5-(4-MORPHOLIN-4-YL-PHENYLSULFANYL)-2,4-QUINAZOLINEDIAMINE'>TQ6</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene>, <scene name='pdbligand=TQ6:5-(4-MORPHOLIN-4-YL-PHENYLSULFANYL)-2,4-QUINAZOLINEDIAMINE'>TQ6</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ia4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ia4 OCA], [https://pdbe.org/1ia4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ia4 RCSB], [https://www.ebi.ac.uk/pdbsum/1ia4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ia4 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ia4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ia4 OCA], [https://pdbe.org/1ia4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ia4 RCSB], [https://www.ebi.ac.uk/pdbsum/1ia4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ia4 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/DYR_CANAX DYR_CANAX] Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Candida albicans]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Howard | [[Category: Howard AJ]] | ||
[[Category: Kuyper | [[Category: Kuyper LF]] | ||
[[Category: Whitlow | [[Category: Whitlow M]] | ||