4ds0: Difference between revisions

← Older edit Newer edit →

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

@@ Line 3: / Line 3: @@
 <StructureSection load='4ds0' size='340' side='right'caption='[[4ds0]], [[Resolution|resolution]] 1.56&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[4ds0]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Rotavirus_sp. Rotavirus sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DS0 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=4DS0 FirstGlance]. <br>
+<table><tr><td colspan='2'>[[4ds0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rotavirus_sp. Rotavirus sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DS0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4DS0 FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A2G:N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE'>A2G</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A2G:N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE'>A2G</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PRD_900132:Blood+group+A+H+type+2+antigen,+beta+anomer'>PRD_900132</scene></td></tr>
-<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4drr|4drr]], [[4drv|4drv]]</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ds0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ds0 OCA], [https://pdbe.org/4ds0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ds0 RCSB], [https://www.ebi.ac.uk/pdbsum/4ds0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ds0 ProSAT]</span></td></tr>
-<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">VP4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10970 Rotavirus sp.])</td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=4ds0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ds0 OCA], [http://pdbe.org/4ds0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ds0 RCSB], [http://www.ebi.ac.uk/pdbsum/4ds0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ds0 ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/Q86169_9REOV Q86169_9REOV]] Outer capsid protein VP5*: forms the spike "foot" and "body". Acts as a membrane permeabilization protein that mediates release of viral particles from endosomal compartments into the cytoplasm. In integrin-dependent strains, VP5* targets the integrin heterodimer ITGA2/ITGB1 for cell attachment.[SAAS:SAAS00136874]  VP8* forms the head of the spikes. It is the viral hemagglutinin and an important target of neutralizing antibodies. In sialic acid-dependent strains, VP8* binds to host cell sialic acid, most probably a ganglioside, providing the initial contact.[SAAS:SAAS00136880]
+[[https://www.uniprot.org/uniprot/Q86169_9REOV Q86169_9REOV]] Outer capsid protein VP5*: forms the spike "foot" and "body". Acts as a membrane permeabilization protein that mediates release of viral particles from endosomal compartments into the cytoplasm. In integrin-dependent strains, VP5* targets the integrin heterodimer ITGA2/ITGB1 for cell attachment.[SAAS:SAAS00136874]  VP8* forms the head of the spikes. It is the viral hemagglutinin and an important target of neutralizing antibodies. In sialic acid-dependent strains, VP8* binds to host cell sialic acid, most probably a ganglioside, providing the initial contact.[SAAS:SAAS00136880]
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
@@ Line 20: / Line 18: @@
 </div>
 <div class="pdbe-citations 4ds0" style="background-color:#fffaf0;"></div>
-==See Also==
-*[[Virus coat proteins 3D structures|Virus coat proteins 3D structures]]
 == References ==
 <references/>
@@ Line 29: / Line 24: @@
 [[Category: Large Structures]]
 [[Category: Rotavirus sp]]
-[[Category: Cortes-Penfield, N W]]
+[[Category: Cortes-Penfield NW]]
-[[Category: Crawford, S E]]
+[[Category: Crawford SE]]
-[[Category: Czako, R]]
+[[Category: Czako R]]
-[[Category: Estes, M K]]
+[[Category: Estes MK]]
-[[Category: Hu, L]]
+[[Category: Hu L]]
-[[Category: Pendu, J Le]]
+[[Category: Le Pendu J]]
-[[Category: Prasad, B V.V]]
+[[Category: Prasad BVV]]
-[[Category: Smith, D F]]
+[[Category: Smith DF]]
-[[Category: Cell attachment factor]]
-[[Category: Galectin-fold]]
-[[Category: Histo blood group antigen]]
-[[Category: Otavirus]]
-[[Category: Viral protein]]