4dpu: Difference between revisions

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==Crystal structure of Staphylococcus epidermidis S192A mevalonate diphosphate decarboxylase complexed with inhibitor 6-FMVAPP and ATPgS==
==Crystal structure of Staphylococcus epidermidis S192A mevalonate diphosphate decarboxylase complexed with inhibitor 6-FMVAPP and ATPgS==
<StructureSection load='4dpu' size='340' side='right' caption='[[4dpu]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
<StructureSection load='4dpu' size='340' side='right'caption='[[4dpu]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4dpu]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"albococcus_epidermidis"_winslow_and_winslow_1908 "albococcus epidermidis" winslow and winslow 1908]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DPU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4DPU FirstGlance]. <br>
<table><tr><td colspan='2'>[[4dpu]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_epidermidis Staphylococcus epidermidis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DPU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4DPU FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AGS:PHOSPHOTHIOPHOSPHORIC+ACID-ADENYLATE+ESTER'>AGS</scene>, <scene name='pdbligand=FM0:(3R)-3-(FLUOROMETHYL)-3-HYDROXY-5-{[(S)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}PENTANOIC+ACID'>FM0</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AGS:PHOSPHOTHIOPHOSPHORIC+ACID-ADENYLATE+ESTER'>AGS</scene>, <scene name='pdbligand=FM0:(3R)-3-(FLUOROMETHYL)-3-HYDROXY-5-{[(S)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}PENTANOIC+ACID'>FM0</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3qt5|3qt5]], [[3qt6|3qt6]], [[3qt7|3qt7]], [[3qt8|3qt8]], [[4dpt|4dpt]], [[4dpw|4dpw]], [[4dpx|4dpx]], [[4dpy|4dpy]], [[4du7|4du7]], [[4du8|4du8]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4dpu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4dpu OCA], [https://pdbe.org/4dpu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4dpu RCSB], [https://www.ebi.ac.uk/pdbsum/4dpu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4dpu ProSAT]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">mvaD ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1282 "Albococcus epidermidis" Winslow and Winslow 1908])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Diphosphomevalonate_decarboxylase Diphosphomevalonate decarboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.33 4.1.1.33] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4dpu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4dpu OCA], [http://pdbe.org/4dpu PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4dpu RCSB], [http://www.ebi.ac.uk/pdbsum/4dpu PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4dpu ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[[https://www.uniprot.org/uniprot/Q9FD73_STAEP Q9FD73_STAEP]]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Albococcus epidermidis winslow and winslow 1908]]
[[Category: Large Structures]]
[[Category: Diphosphomevalonate decarboxylase]]
[[Category: Staphylococcus epidermidis]]
[[Category: Barta, M L]]
[[Category: Barta ML]]
[[Category: Geisbrecht, B V]]
[[Category: Geisbrecht BV]]
[[Category: McWhorter, W J]]
[[Category: McWhorter WJ]]
[[Category: Ghmp kinase family]]
[[Category: Lyase-lyase inhibitor complex]]

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