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==Crystal structure of human Peptidyl-prolyl cis-trans isomerase FKBP14==
==Crystal structure of human Peptidyl-prolyl cis-trans isomerase FKBP14==
<StructureSection load='4dip' size='340' side='right' caption='[[4dip]], [[Resolution|resolution]] 1.82&Aring;' scene=''>
<StructureSection load='4dip' size='340' side='right'caption='[[4dip]], [[Resolution|resolution]] 1.82&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4dip]] is a 10 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DIP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4DIP FirstGlance]. <br>
<table><tr><td colspan='2'>[[4dip]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DIP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4DIP FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">FKBP14, FKBP22, UNQ322/PRO381 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4dip FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4dip OCA], [https://pdbe.org/4dip PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4dip RCSB], [https://www.ebi.ac.uk/pdbsum/4dip PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4dip ProSAT]</span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Peptidylprolyl_isomerase Peptidylprolyl isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.2.1.8 5.2.1.8] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4dip FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4dip OCA], [http://pdbe.org/4dip PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4dip RCSB], [http://www.ebi.ac.uk/pdbsum/4dip PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4dip ProSAT]</span></td></tr>
</table>
</table>
== Disease ==
== Disease ==
[[http://www.uniprot.org/uniprot/FKB14_HUMAN FKB14_HUMAN]] Ehlers-Danlos syndrome, kyphoscoliotic and deafness type. The disease is caused by mutations affecting the gene represented in this entry.  
[[https://www.uniprot.org/uniprot/FKB14_HUMAN FKB14_HUMAN]] Ehlers-Danlos syndrome, kyphoscoliotic and deafness type. The disease is caused by mutations affecting the gene represented in this entry.
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/FKB14_HUMAN FKB14_HUMAN]] PPIases accelerate the folding of proteins during protein synthesis.  
[[https://www.uniprot.org/uniprot/FKB14_HUMAN FKB14_HUMAN]] PPIases accelerate the folding of proteins during protein synthesis.


==See Also==
==See Also==
*[[FK506 binding protein|FK506 binding protein]]
*[[FKBP 3D structures|FKBP 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Peptidylprolyl isomerase]]
[[Category: Large Structures]]
[[Category: Arrowsmith, C H]]
[[Category: Arrowsmith CH]]
[[Category: Bountra, C]]
[[Category: Bountra C]]
[[Category: Delft, F von]]
[[Category: Edwards A]]
[[Category: Edwards, A]]
[[Category: Filippakopoulos P]]
[[Category: Filippakopoulos, P]]
[[Category: Goubin S]]
[[Category: Goubin, S]]
[[Category: Kiyani W]]
[[Category: Kiyani, W]]
[[Category: Krojer T]]
[[Category: Krojer, T]]
[[Category: Muniz JRC]]
[[Category: Muniz, J R.C]]
[[Category: Oppermann U]]
[[Category: Oppermann, U]]
[[Category: Yue WW]]
[[Category: Structural genomic]]
[[Category: Zschocke J]]
[[Category: Yue, W W]]
[[Category: Von Delft F]]
[[Category: Zschocke, J]]
[[Category: Isomerase]]
[[Category: Peptidyl-prolyl cis-trans isomerase]]
[[Category: Sgc]]

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