4ddl: Difference between revisions

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 ==PDE10a Crystal Structure Complexed with Novel Inhibitor==
-<StructureSection load='4ddl' size='340' side='right' caption='[[4ddl]], [[Resolution|resolution]] 2.07&Aring;' scene=''>
+<StructureSection load='4ddl' size='340' side='right'caption='[[4ddl]], [[Resolution|resolution]] 2.07&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[4ddl]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DDL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4DDL FirstGlance]. <br>
+<table><tr><td colspan='2'>[[4ddl]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DDL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4DDL FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=0JQ:2-{1-[5-(6,7-DIMETHOXYCINNOLIN-4-YL)-3-METHYLPYRIDIN-2-YL]PIPERIDIN-4-YL}PROPAN-2-OL'>0JQ</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0JQ:2-{1-[5-(6,7-DIMETHOXYCINNOLIN-4-YL)-3-METHYLPYRIDIN-2-YL]PIPERIDIN-4-YL}PROPAN-2-OL'>0JQ</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2oup|2oup]]</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ddl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ddl OCA], [https://pdbe.org/4ddl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ddl RCSB], [https://www.ebi.ac.uk/pdbsum/4ddl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ddl ProSAT]</span></td></tr>
-<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PDE10A ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ddl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ddl OCA], [http://pdbe.org/4ddl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ddl RCSB], [http://www.ebi.ac.uk/pdbsum/4ddl PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ddl ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/PDE10_HUMAN PDE10_HUMAN]] Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. Can hydrolyze both cAMP and cGMP, but has higher affinity for cAMP and is more efficient with cAMP as substrate.<ref>PMID:17389385</ref>
+[[https://www.uniprot.org/uniprot/PDE10_HUMAN PDE10_HUMAN]] Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. Can hydrolyze both cAMP and cGMP, but has higher affinity for cAMP and is more efficient with cAMP as substrate.<ref>PMID:17389385</ref>
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
@@ Line 22: / Line 20: @@
 ==See Also==
-*[[Phosphodiesterase|Phosphodiesterase]]
+*[[Phosphodiesterase 3D structures|Phosphodiesterase 3D structures]]
 == References ==
 <references/>
 __TOC__
 </StructureSection>
-[[Category: Human]]
+[[Category: Homo sapiens]]
-[[Category: Chmait, S]]
+[[Category: Large Structures]]
-[[Category: Jordan, S]]
+[[Category: Chmait S]]
-[[Category: Zhang, J]]
+[[Category: Jordan S]]
-[[Category: Hydrolase]]
+[[Category: Zhang J]]
-[[Category: Hydrolase-hydrolase inhibitor complex]]
-[[Category: Phosphodiesterase 10a]]