4d3b: Difference between revisions

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<StructureSection load='4d3b' size='340' side='right'caption='[[4d3b]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
<StructureSection load='4d3b' size='340' side='right'caption='[[4d3b]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4d3b]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Buffalo_rat Buffalo rat]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4D3B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4D3B FirstGlance]. <br>
<table><tr><td colspan='2'>[[4d3b]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4D3B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4D3B FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=6J0:N-[2-(3-FLUOROPHENYL)ETHYL]-N-[2-(1H-IMIDAZOL-1-YL)PYRIMIDIN-4-YL]ETHANE-1,2-DIAMINE'>6J0</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=H4B:5,6,7,8-TETRAHYDROBIOPTERIN'>H4B</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6J0:N-[2-(3-FLUOROPHENYL)ETHYL]-N-[2-(1H-IMIDAZOL-1-YL)PYRIMIDIN-4-YL]ETHANE-1,2-DIAMINE'>6J0</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=H4B:5,6,7,8-TETRAHYDROBIOPTERIN'>H4B</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4d2y|4d2y]], [[4d2z|4d2z]], [[4d30|4d30]], [[4d31|4d31]], [[4d32|4d32]], [[4d33|4d33]], [[4d34|4d34]], [[4d35|4d35]], [[4d36|4d36]], [[4d37|4d37]], [[4d38|4d38]], [[4d39|4d39]], [[4d3a|4d3a]], [[4v3u|4v3u]], [[4v3v|4v3v]], [[4v3w|4v3w]], [[4v3x|4v3x]], [[4v3y|4v3y]], [[4v3z|4v3z]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4d3b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4d3b OCA], [https://pdbe.org/4d3b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4d3b RCSB], [https://www.ebi.ac.uk/pdbsum/4d3b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4d3b ProSAT]</span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Nitric-oxide_synthase_(NADPH_dependent) Nitric-oxide synthase (NADPH dependent)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.13.39 1.14.13.39] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4d3b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4d3b OCA], [http://pdbe.org/4d3b PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4d3b RCSB], [http://www.ebi.ac.uk/pdbsum/4d3b PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4d3b ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/NOS1_RAT NOS1_RAT]] Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter. Inhibitory transmitter for non-adrenergic and non-cholinergic nerves in the colorectum. Probably has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such SRR. Inhibitory transmitter for non-adrenergic and non-cholinergic nerves in the colorectum.  
[[https://www.uniprot.org/uniprot/NOS1_RAT NOS1_RAT]] Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter. Inhibitory transmitter for non-adrenergic and non-cholinergic nerves in the colorectum. Probably has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such SRR. Inhibitory transmitter for non-adrenergic and non-cholinergic nerves in the colorectum.
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== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
*[[Nitric Oxide Synthase|Nitric Oxide Synthase]]
*[[Nitric Oxide Synthase 3D structures|Nitric Oxide Synthase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Buffalo rat]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Li, H]]
[[Category: Rattus norvegicus]]
[[Category: Poulos, T L]]
[[Category: Li H]]
[[Category: Inhibitor complex]]
[[Category: Poulos TL]]
[[Category: Nitric oxide synthase]]
[[Category: Oxidoreductase]]

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