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==1.6 Angstrom Resolution Crystal Structure of SARS-CoV-2 Nucleocapsid dimerization domain, pH 5.0== | ==1.6 Angstrom Resolution Crystal Structure of SARS-CoV-2 Nucleocapsid dimerization domain, pH 5.0== | ||
<StructureSection load='7vbe' size='340' side='right'caption='[[7vbe]]' scene=''> | <StructureSection load='7vbe' size='340' side='right'caption='[[7vbe]], [[Resolution|resolution]] 1.59Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7VBE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7VBE FirstGlance]. <br> | <table><tr><td colspan='2'>[[7vbe]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Severe_acute_respiratory_syndrome_coronavirus_2 Severe acute respiratory syndrome coronavirus 2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7VBE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7VBE FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7vbe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7vbe OCA], [https://pdbe.org/7vbe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7vbe RCSB], [https://www.ebi.ac.uk/pdbsum/7vbe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7vbe ProSAT]</span></td></tr> | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7vbe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7vbe OCA], [https://pdbe.org/7vbe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7vbe RCSB], [https://www.ebi.ac.uk/pdbsum/7vbe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7vbe ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | |||
[[https://www.uniprot.org/uniprot/NCAP_SARS2 NCAP_SARS2]] Packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication. | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Severe acute respiratory syndrome coronavirus 2]] | |||
[[Category: Li J]] | [[Category: Li J]] | ||
[[Category: Zhang J]] | [[Category: Zhang J]] | ||
[[Category: Zhong FL]] | [[Category: Zhong FL]] | ||
[[Category: Zhou XL]] | [[Category: Zhou XL]] | ||
Revision as of 09:47, 8 September 2022
1.6 Angstrom Resolution Crystal Structure of SARS-CoV-2 Nucleocapsid dimerization domain, pH 5.01.6 Angstrom Resolution Crystal Structure of SARS-CoV-2 Nucleocapsid dimerization domain, pH 5.0
Structural highlights
Function[NCAP_SARS2] Packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication. |
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