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==== | ==Cryo-EM structure of the GDP-bound dopamine receptor 1 and mini-Gs complex with Nb35== | ||
<StructureSection load='7f1o' size='340' side='right'caption='[[7f1o]]' scene=''> | <StructureSection load='7f1o' size='340' side='right'caption='[[7f1o]], [[Resolution|resolution]] 3.13Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br> | <table><tr><td colspan='2'>[[7f1o]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7F1O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7F1O FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7f1o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7f1o OCA], [https://pdbe.org/7f1o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7f1o RCSB], [https://www.ebi.ac.uk/pdbsum/7f1o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7f1o ProSAT]</span></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=LDP:L-DOPAMINE'>LDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7f1o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7f1o OCA], [https://pdbe.org/7f1o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7f1o RCSB], [https://www.ebi.ac.uk/pdbsum/7f1o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7f1o ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | |||
[[https://www.uniprot.org/uniprot/DRD1_HUMAN DRD1_HUMAN]] Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase. | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: | [[Category: Synthetic construct]] | ||
[[Category: Xiao T]] | |||
[[Category: Zheng S]] | |||
Revision as of 09:21, 8 September 2022
Cryo-EM structure of the GDP-bound dopamine receptor 1 and mini-Gs complex with Nb35Cryo-EM structure of the GDP-bound dopamine receptor 1 and mini-Gs complex with Nb35
Structural highlights
Function[DRD1_HUMAN] Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase. |
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