7r5c: Difference between revisions
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==== | ==Structure of E.coli Class 2 L-asparaginase EcAIII, mutant RDM1-29 (G206C, R207S, D210L, S211V)== | ||
<StructureSection load='7r5c' size='340' side='right'caption='[[7r5c]]' scene=''> | <StructureSection load='7r5c' size='340' side='right'caption='[[7r5c]], [[Resolution|resolution]] 2.20Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br> | <table><tr><td colspan='2'>[[7r5c]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7R5C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7R5C FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7r5c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7r5c OCA], [https://pdbe.org/7r5c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7r5c RCSB], [https://www.ebi.ac.uk/pdbsum/7r5c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7r5c ProSAT]</span></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7r5c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7r5c OCA], [https://pdbe.org/7r5c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7r5c RCSB], [https://www.ebi.ac.uk/pdbsum/7r5c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7r5c ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | |||
[[https://www.uniprot.org/uniprot/IAAA_ECOLI IAAA_ECOLI]] Degrades proteins damaged by L-isoaspartyl residue formation (also known as beta-Asp residues). Degrades L-isoaspartyl-containing di- and maybe also tripeptides. Also has L-asparaginase activity, although this may not be its principal function.<ref>PMID:11988085</ref> May be involved in glutathione, and possibly other peptide, transport, although these results could also be due to polar effects of disruption.<ref>PMID:11988085</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Escherichia coli]] | |||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: | [[Category: Barciszewski J]] | ||
[[Category: Imiolczyk B]] | |||
[[Category: Jaskolski M]] | |||
[[Category: Loch JI]] | |||