7vdm: Difference between revisions
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==== | ==Cryo-EM structure of pseudoallergen receptor MRGPRX2 complex with substance P== | ||
<StructureSection load='7vdm' size='340' side='right'caption='[[7vdm]]' scene=''> | <StructureSection load='7vdm' size='340' side='right'caption='[[7vdm]], [[Resolution|resolution]] 2.98Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br> | <table><tr><td colspan='2'>[[7vdm]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7VDM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7VDM FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7vdm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7vdm OCA], [https://pdbe.org/7vdm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7vdm RCSB], [https://www.ebi.ac.uk/pdbsum/7vdm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7vdm ProSAT]</span></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CLR:CHOLESTEROL'>CLR</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7vdm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7vdm OCA], [https://pdbe.org/7vdm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7vdm RCSB], [https://www.ebi.ac.uk/pdbsum/7vdm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7vdm ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | |||
[[https://www.uniprot.org/uniprot/GNAI1_HUMAN GNAI1_HUMAN]] Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta-adrenergic stimuli. The inactive GDP-bound form prevents the association of RGS14 with centrosomes and is required for the translocation of RGS14 from the cytoplasm to the plasma membrane. May play a role in cell division.<ref>PMID:17635935</ref> <ref>PMID:17264214</ref> | |||
==See Also== | |||
*[[Transducin 3D structures|Transducin 3D structures]] | |||
== References == | |||
<references/> | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: | [[Category: Li Y]] | ||
[[Category: Yang F]] | |||