7n5u: Difference between revisions

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OCA

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-====
+==ZBTB7A Zinc Finger Domain Bound to DNA Duplex Containing GGACCC (Oligo 21)==
-<StructureSection load='7n5u' size='340' side='right'caption='[[7n5u]]' scene=''>
+<StructureSection load='7n5u' size='340' side='right'caption='[[7n5u]], [[Resolution|resolution]] 2.86&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>
+<table><tr><td colspan='2'>[[7n5u]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7N5U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7N5U FirstGlance]. <br>
-</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7n5u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7n5u OCA], [https://pdbe.org/7n5u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7n5u RCSB], [https://www.ebi.ac.uk/pdbsum/7n5u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7n5u ProSAT]</span></td></tr>
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7n5u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7n5u OCA], [https://pdbe.org/7n5u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7n5u RCSB], [https://www.ebi.ac.uk/pdbsum/7n5u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7n5u ProSAT]</span></td></tr>
 </table>
+== Function ==
+[[https://www.uniprot.org/uniprot/ZBT7A_HUMAN ZBT7A_HUMAN]] Plays a key role in the instruction of early lymphoid progenitors to develop into B lineage by repressing T-cell instructive Notch signals (By similarity). Specifically represses the transcription of the CDKN2A gene. Efficiently abrogates E2F1-dependent CDKN2A transactivation/de-repression. Binds to the consensus sequence 5'-[GA][CA]GACCCCCCCCC-3' (By similarity).
 __TOC__
 </StructureSection>
+[[Category: Homo sapiens]]
 [[Category: Large Structures]]
-[[Category: Z-disk]]
+[[Category: Cheng X]]
+[[Category: Horton JR]]
+[[Category: Ren R]]