4bpv: Difference between revisions
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<StructureSection load='4bpv' size='340' side='right'caption='[[4bpv]], [[Resolution|resolution]] 2.00Å' scene=''> | <StructureSection load='4bpv' size='340' side='right'caption='[[4bpv]], [[Resolution|resolution]] 2.00Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4bpv]] is a 6 chain structure with sequence from [ | <table><tr><td colspan='2'>[[4bpv]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BPV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4BPV FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=OFH:(4R)-4-[(2-CHLORO-4-{[(2S)-1,1,1-TRIFLUOROPROPAN-2-YL]OXY}PHENYL)SULFONYL]-N-{1-[(E)-IMINOMETHYL]CYCLOPROPYL}-1-{[1-(TRIFLUOROMETHYL)CYCLOPROPYL]CARBONYL}-L-PROLINAMIDE'>OFH</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=OFH:(4R)-4-[(2-CHLORO-4-{[(2S)-1,1,1-TRIFLUOROPROPAN-2-YL]OXY}PHENYL)SULFONYL]-N-{1-[(E)-IMINOMETHYL]CYCLOPROPYL}-1-{[1-(TRIFLUOROMETHYL)CYCLOPROPYL]CARBONYL}-L-PROLINAMIDE'>OFH</scene></td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Cathepsin_S Cathepsin S], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.27 3.4.22.27] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4bpv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bpv OCA], [https://pdbe.org/4bpv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4bpv RCSB], [https://www.ebi.ac.uk/pdbsum/4bpv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4bpv ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[[ | [[https://www.uniprot.org/uniprot/CATS_MOUSE CATS_MOUSE]] Thiol protease. Key protease responsible for the removal of the invariant chain from MHC class II molecules. The bond-specificity of this proteinase is in part similar to the specificities of cathepsin L and cathepsin N. | ||
==See Also== | ==See Also== | ||
*[[Cathepsin|Cathepsin]] | *[[Cathepsin 3D structures|Cathepsin 3D structures]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
Revision as of 10:21, 31 August 2022
MOUSE CATHEPSIN S WITH COVALENT LIGANDMOUSE CATHEPSIN S WITH COVALENT LIGAND
Structural highlights
Function[CATS_MOUSE] Thiol protease. Key protease responsible for the removal of the invariant chain from MHC class II molecules. The bond-specificity of this proteinase is in part similar to the specificities of cathepsin L and cathepsin N. See Also |
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