4am8: Difference between revisions

From Proteopedia
Jump to navigation Jump to search
← Older editNewer edit →
No edit summary
No edit summary
Line 3: Line 3:
<StructureSection load='4am8' size='340' side='right'caption='[[4am8]], [[Resolution|resolution]] 1.99&Aring;' scene=''>
<StructureSection load='4am8' size='340' side='right'caption='[[4am8]], [[Resolution|resolution]] 1.99&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4am8]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/"enterococcus_proteiformis"_thiercelin_and_jouhaud_1903 "enterococcus proteiformis" thiercelin and jouhaud 1903]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AM8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4AM8 FirstGlance]. <br>
<table><tr><td colspan='2'>[[4am8]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/"enterococcus_proteiformis"_thiercelin_and_jouhaud_1903 "enterococcus proteiformis" thiercelin and jouhaud 1903]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AM8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4AM8 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GAI:GUANIDINE'>GAI</scene>, <scene name='pdbligand=GLN:GLUTAMINE'>GLN</scene>, <scene name='pdbligand=ILE:ISOLEUCINE'>ILE</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>, <scene name='pdbligand=PAO:N-(PHOSPHONOACETYL)-L-ORNITHINE'>PAO</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GAI:GUANIDINE'>GAI</scene>, <scene name='pdbligand=GLN:GLUTAMINE'>GLN</scene>, <scene name='pdbligand=ILE:ISOLEUCINE'>ILE</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>, <scene name='pdbligand=PAO:N-(PHOSPHONOACETYL)-L-ORNITHINE'>PAO</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4a8h|4a8h]], [[4a8p|4a8p]], [[4a8t|4a8t]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[4a8h|4a8h]], [[4a8p|4a8p]], [[4a8t|4a8t]]</div></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Putrescine_carbamoyltransferase Putrescine carbamoyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.3.6 2.1.3.6] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Putrescine_carbamoyltransferase Putrescine carbamoyltransferase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.3.6 2.1.3.6] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4am8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4am8 OCA], [http://pdbe.org/4am8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4am8 RCSB], [http://www.ebi.ac.uk/pdbsum/4am8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4am8 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4am8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4am8 OCA], [https://pdbe.org/4am8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4am8 RCSB], [https://www.ebi.ac.uk/pdbsum/4am8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4am8 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/PTC_ENTFA PTC_ENTFA]] Catalyzes the phosphorolysis of N-carbamoylputrescine to form carbamoyl phosphate and putrescine. Is involved in the degradation pathway of the polyamine agmatine. Also has weak activity with ornithine and cadaverine.<ref>PMID:4621632</ref>   
[[https://www.uniprot.org/uniprot/PTC_ENTFA PTC_ENTFA]] Catalyzes the phosphorolysis of N-carbamoylputrescine to form carbamoyl phosphate and putrescine. Is involved in the degradation pathway of the polyamine agmatine. Also has weak activity with ornithine and cadaverine.<ref>PMID:4621632</ref>   
== References ==
== References ==
<references/>
<references/>
Line 16: Line 16:
</StructureSection>
</StructureSection>
[[Category: Enterococcus proteiformis thiercelin and jouhaud 1903]]
[[Category: Enterococcus proteiformis thiercelin and jouhaud 1903]]
[[Category: Large Structures]]
[[Category: Putrescine carbamoyltransferase]]
[[Category: Putrescine carbamoyltransferase]]
[[Category: Polo, L M]]
[[Category: Polo, L M]]

Revision as of 08:38, 25 August 2022

Crystal structure of the R54G mutant of putrescine transcarbamylase from Enterococcus faecalis bound to a curing guanidinium ionCrystal structure of the R54G mutant of putrescine transcarbamylase from Enterococcus faecalis bound to a curing guanidinium ion

Structural highlights

4am8 is a 6 chain structure with sequence from "enterococcus_proteiformis"_thiercelin_and_jouhaud_1903 "enterococcus proteiformis" thiercelin and jouhaud 1903. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:, , , , ,
Activity:Putrescine carbamoyltransferase, with EC number 2.1.3.6
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[PTC_ENTFA] Catalyzes the phosphorolysis of N-carbamoylputrescine to form carbamoyl phosphate and putrescine. Is involved in the degradation pathway of the polyamine agmatine. Also has weak activity with ornithine and cadaverine.[1]

References

  1. ↑ Roon RJ, Barker HA. Fermentation of agmatine in Streptococcus faecalis: occurrence of putrescine transcarbamoylase. J Bacteriol. 1972 Jan;109(1):44-50. PMID:4621632

4am8, resolution 1.99Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA
Retrieved from "https://proteopedia.openfox.io/wiki/index.php?title=4am8&oldid=3608649"