4ala: Difference between revisions

<table><tr><td colspan='2'>[[4ala]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Dengue_virus_3 Dengue virus 3] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ALA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ALA FirstGlance]. <br>

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>

<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4al8|4al8]], [[4am0|4am0]]</td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ala FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ala OCA], [http://pdbe.org/4ala PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ala RCSB], [http://www.ebi.ac.uk/pdbsum/4ala PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ala ProSAT]</span></td></tr>

[[http://www.uniprot.org/uniprot/Q7TGD1_9FLAV Q7TGD1_9FLAV]] Envelope protein E binding to host cell surface receptor is followed by virus internalization through clathrin-mediated endocytosis. Envelope protein E is subsequently involved in membrane fusion between virion and host late endosomes. Synthesized as a homodimer with prM which acts as a chaperone for envelope protein E. After cleavage of prM, envelope protein E dissociate from small envelope protein M and homodimerizes (By similarity).[SAAS:SAAS026470_004_099774]