3vbo: Difference between revisions

No edit summary
No edit summary
Line 1: Line 1:


==Crystal structure of formaldehyde treated empty human Enterovirus 71 particle (cryo at 100K)==
==Crystal structure of formaldehyde treated empty human Enterovirus 71 particle (cryo at 100K)==
<StructureSection load='3vbo' size='340' side='right' caption='[[3vbo]], [[Resolution|resolution]] 2.88&Aring;' scene=''>
<StructureSection load='3vbo' size='340' side='right'caption='[[3vbo]], [[Resolution|resolution]] 2.88&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3vbo]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_enterovirus_71 Human enterovirus 71]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VBO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3VBO FirstGlance]. <br>
<table><tr><td colspan='2'>[[3vbo]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_enterovirus_71 Human enterovirus 71]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VBO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3VBO FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3vbf|3vbf]], [[3vbh|3vbh]], [[3vbr|3vbr]], [[3vbs|3vbs]], [[3vbu|3vbu]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3vbf|3vbf]], [[3vbh|3vbh]], [[3vbr|3vbr]], [[3vbs|3vbs]], [[3vbu|3vbu]]</div></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3vbo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vbo OCA], [http://pdbe.org/3vbo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3vbo RCSB], [http://www.ebi.ac.uk/pdbsum/3vbo PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3vbo ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3vbo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vbo OCA], [https://pdbe.org/3vbo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3vbo RCSB], [https://www.ebi.ac.uk/pdbsum/3vbo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3vbo ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/B2ZUN0_9ENTO B2ZUN0_9ENTO]] Protein 2C associates with and induces structural rearrangements of intracellular membranes. It displays RNA-binding, nucleotide binding and NTPase activities (By similarity).[SAAS:SAAS000199_004_016611]  Protein 3C is a cysteine protease that generates mature viral proteins from the precursor polyprotein. In addition to its proteolytic activity, it binds to viral RNA, and thus influences viral genome replication. RNA and substrate bind co-operatively to the protease (By similarity).[SAAS:SAAS000199_004_042266]  RNA-directed RNA polymerase 3D-POL replicates genomic and antigenomic RNA by recognizing replications specific signals (By similarity).[SAAS:SAAS000199_004_010047]  
[[https://www.uniprot.org/uniprot/B2ZUN0_9ENTO B2ZUN0_9ENTO]] Protein 2C associates with and induces structural rearrangements of intracellular membranes. It displays RNA-binding, nucleotide binding and NTPase activities (By similarity).[SAAS:SAAS000199_004_016611]  Protein 3C is a cysteine protease that generates mature viral proteins from the precursor polyprotein. In addition to its proteolytic activity, it binds to viral RNA, and thus influences viral genome replication. RNA and substrate bind co-operatively to the protease (By similarity).[SAAS:SAAS000199_004_042266]  RNA-directed RNA polymerase 3D-POL replicates genomic and antigenomic RNA by recognizing replications specific signals (By similarity).[SAAS:SAAS000199_004_010047]  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 21: Line 21:


==See Also==
==See Also==
*[[Virus coat protein|Virus coat protein]]
*[[Virus coat proteins 3D structures|Virus coat proteins 3D structures]]
== References ==
== References ==
<references/>
<references/>
Line 27: Line 27:
</StructureSection>
</StructureSection>
[[Category: Human enterovirus 71]]
[[Category: Human enterovirus 71]]
[[Category: Large Structures]]
[[Category: Axford, D]]
[[Category: Axford, D]]
[[Category: Evans, G]]
[[Category: Evans, G]]

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA